Dr. Robert G. Zamenhof
CONTACT INFORMATION
PO Box 153
South Woodstock
VT 05071
Tel: (802) 457-5861
Fax: (802) 419-8265
Email: [email protected]
PLACE OF BIRTH
Kidugala, Tanzania, East Africa
EDUCATION
1966-1970 B.Sc. Caledonian University (U.K.) (Electrical Engineering)
1971-1972 M.Sc. University of Strathclyde (U.K.) (Bioengineering)
1973-1977 Ph.D. Massachusetts Institute of Technology (Nuclear Engineering & Applied
Radiation Physics)
POSTDOCTORAL TRAINING
1976-1978 Research Fellow in Radiological Physics, Massachusetts General Hospital, Harvard
Medical School
BOARD CERTIFICATIONS
1985 American Board of Radiology, certification in Radiological Physics
(includes three areas: therapeutic radiation physics, diagnostic radiation physics,
and nuclear medicine physics)
2015 American Portable Nuclear Gauge Association, certified user
FULL-TIME ACADEMIC APPOINTMENTS
1976-1979 Research Fellow in Physics, Harvard Medical School, Massachusetts General
Hospital
1978-1982 Assistant Professor of Radiation Oncology & Diagnostic Radiology, Tufts School of
Medicine
1982-1989 Associate Professor of Radiation Oncology and Diagnostic Radiology Tufts School
of Medicine
1989-1996 Professor of Radiology (Medical Physics), Tufts School of Medicine
1996-2004 Associate Professor of Radiology, Harvard Medical School
2003-2007 Professor of Radiation Oncology, Tufts School of Medicine
2004-2007 Vice Chairman & Director of Research, Department of Radiation Oncology, Tufts University School of Medicine
PART-TIME & VISITING ACADEMIC APPOINTMENTS
1977-1980 Adjunct Assistant Professor of Engineering, Boston University
1987-2003 Research Affiliate, Department of Nuclear Engineering, MIT
1997 Visiting Professor, Wayne State University, Department of Physics
1994-2007 Visiting Scientist, Department of Nuclear Engineering, MIT
2006 Visiting Professor, Department of Physics, University of Buenos Aires
2007-2008 Visiting Professor, Department of Physics, Indiana University
HOSPITAL & OTHER APPOINTMENTS
1979-1981 Chief, Radiotherapy Treatment Planning Section, Dept. of Radiation Oncology,
Tufts-New England Medical Center
1981-1995 Chief, Radiological Sciences Section, Dept. of Radiation Oncology, New England
Medical Center
1996-2003 Chief, Radiological Physics Section, Department of Radiology, Beth Israel
Deaconess Medical Center
2003-2007 Director, Division of Radiological Sciences, Department of Radiation Oncology,
Tufts-New England Medical Center
2004-2007 Vice Chairman & Director of Research, Department of Radiation Oncology, Tufts
School of Medicine
2007-2008 Interim Director of Proton Physics, Midwest Proton Radiotherapy Institute,
Bloomington, Indiana
2011-2013 Radiation Safety Officer, St. Francis Hospital & Medical Center, Hartford, CT
2016-2016 Director of Medical Physics, Petrone Associates, LLC, NYC, NY
AWARDS & HONORS
1971-1972 British Science Research Council Scholarship (U.K.)
1973-1975 Harvard-MIT Health Science and Technology Fellowship
1975-1977 MIT Health Sciences Fund Fellowship
1976 Sigma-Xi Research Society of North America
1987 Co-Recipient, Sylvia-Sorkin-Greenfield award for best paper in Medical Physics in 1987
2002 Elected to Fellowship of the AAPM
2011 Elected to Fellowship of the ACMP
COMMITTEE MEMBERSHIPS: REGIONAL, NATIONAL & INTERNATIONAL
1979-1982 Member of NCRP Scientific Committee-55 (Experimental Basis for Absorbed
Dose Calculations in Medical Uses of Radionuclides)
1980-1981 Member of Advisory Committee on Research, MIT Nuclear Reactor Laboratory
1981-1983 Member of American Association of Physicists in Medicine (AAPM) International
Affairs Committee
1982-1985 Member of AAPM NMR Committee
1982-1985 Member of AAPM Publications Committee
1982-1883 Member of International Atomic Energy Agency’s Advisory Panel on Nuclear
Techniques in Developing Countries
1982-1983 Chairman, NE Chapter AAPM Committee on Education (including organization of
a two-day symposium on digital angiography (with ACR CME accreditation)
1982-1985 Editor, AAPM Newsletter
1983-1984 President, New England Chapter, AAPM
1986-1987 Member, ACR Committee on Quality Assurance and Acceptance Testing of
Radiology Equipment
1986-1990 Chairman, AAPM Task Group on Bone Density Measurement
1993-1994 Member, U.S. D.O.E. Coordinating Committee for Neutron Capture Therapy
Research
1992-1995 Member of Advisory Committee for NIH Program Project Grant (Dr. Richard
Pierson PI) titled, Methods for High-Precision In Vivo Neutron Activation Analysis
for Body Composition Analysis
1990-2001 Member, Board of Councilors, International Society for Neutron Capture Therapy
1996-2014 Oral Examiner in Radiological Physics, American Board of Radiology
1997-2005 Oral Examiner in Diagnostic Physics, American College of Medical Physics
1997-1999 Associate Editor, Journal of Medical Physics
1998-2007 Panel Chairman, Diagnostic Imaging Physics, American Board of Medical Physics
1998-2005 Member, Executive Board, International Society for Neutron Capture Therapy
1998-2007 Member, Executive Board, American College of Medical Physics
2002-2004 President, International Society for Neutron Capture Therapy
2002-2005 Member, AAPM Board of Chancellors
TUFTS SCHOOL OF MEDICINE & NEW ENGLAND MEDICAL CENTER
1986-1987 Interviewer for Tufts University School of Medicine Admissions Committee
1980-1995 Volunteer Interpreter (Polish Language) for New England Medical Center, Social Services Department
1990-1991 Member of President’s Task Group on Research Goals of NEMC
1990-1991 Department of Radiation Oncology’s representative to Tufts Faculty Senate
1991-1996 Member of Department of Radiation Oncology’s Executive Committee
2003-2007 Member of NEMC’s Radiation Safety Committee
2004-2007 Member of Department of Radiation Oncology’s Executive Committee
2004-2007 Department of Radiation Oncology’s representative to Tufts Faculty Senate
HARVARD MEDICAL SCHOOL & BETH ISRAEL DEACONESS MEDICAL CENTER
1996-2003 Member of BIDMC Radiation Safety Committee
1996-2003 Member of BIDMC RSC Radiation Dosimetry Subcommittee
1996-2003 Member of BIDMC RDRC Committee
1998-2003 Member of BIDMC Committee on Clinical Investigations (IRB)
1997-2003 Member of Department of Radiology’s Grant Review & Faculty Mentorship Committee
2001-2003 Member of Department of Radiology’s Strategic Research Planning Committee
2004-2007 Member of Tufts-NEMC Radiation Safety Committee
MEMBERSHIPS IN PROFESSIONAL SOCIETIES
American Association of Physicists in Medicine - Full Member & Fellow
American College of Medical Physics - Full Member & Fellow
Biomedical Engineering Society -- Senior Member
American College of Radiology – Member, Diplomate, Oral Examiner
Institution of Electronic and Radio Engineers (U.K.) - Member
New England Roentgen Ray Society – Member and Physics Instructor in Residence
New England AAPM Chapter - Member
New England AAPM Chapter - President 1982-1983
International Society for Neutron Capture Therapy - Founding Member, President-Elect (2000-2002)
International Society for Neutron Capture Therapy - President 2002-2004
American Society for Therapeutic Radiology & Oncology – Member
Proton Therapy Combined Oncology Group - Member
PRESENT & PAST RESEARCH INTERESTS
Neutron Capture Therapy: micro-dosimetry, treatment planning, nuclear assay, epithermal beam development, animal & human studies, research program management. This has been my main research activity throughout a large part of my academic career.
CT-based bone density measurement techniques: development, implementation, and optimization (co-inventor of QCT, early researcher on dual-energy CT applications).
Development of dual-energy digital mammography using a molybdenum contrast agent (inventor). Patent applied for.
Development of dual-energy digital mammography using iodine as a contrast agent and X-ray spectra produced by tellurium and cerium (inventor). Patent applied for.
Algorithms for monitoring of individual patient exposures from x-ray procedures. RadComp, an x-ray radiation dose application (inventor).
The deuteron as a proton-complementary particle for treatment of eye tumors and other shallow tumors where targeting precision is critical (inventor). Patent applied for.
RESEARCH UNDER FEDERAL & PRIVATE GRANT SUPPORT
[Over $20,000,000 in grants & contracts awarded between 1982 & 2003 as a principal investigator]
1982-1983 USDA "Measurement of Body Elemental Composition by Photon Activation Analysis", Principal Investigator, $20,000.
1985-1986 Siemens Corporation "Development of Software for the DR3 CT Scanner for automatic analysis of bone density scans”. Principal Investigator, $20,000.
1987-1990 DOE "Preclinical and Clinical Investigations of Neutron Capture Therapy", Principal Investigator & Program Director, $600,000 x3 = $1,800,000.
1990-1993 DOE "Renewal Grant for NEMC-MIT Preclinical Program in Neutron Capture Therapy", Principal Investigator & Program Director, $1,100,000 x3 = $3,300,000.
1991-1992 DOE "Conference Grant to Support an International Workshop in Macro- and Micro-Dosimetry & Treatment Planning”. Principal Investigator, $40,000.
1993-1995 Herbert M. Karol Cancer Foundation "Microdistribution & Microdosimetry of Boron Compounds for Use in Boron Neutron Capture Therapy of Brain Tumors", Principal Investigator, $20,000.
1993-1996 DOE 1 year Grant Extension for NEMC-MIT Preclinical Program in Neutron Capture Therapy", Principal Investigator & Program Director, $1,100,000.
1994-1998 DOE "Continuation of Research Program in Neutron Capture Therapy at NEMC & MIT", Principal Investigator & Program Director, $1,100,000 x3 = $3,300,000.
1996-1998 DOE "Acceleration of the MCNP Los Alamos Monte Carlo Code for Use in Treatment Planning for Boron Neutron Capture Therapy", Investigator (Dr. Guy Estes, LANL, Principal Investigator), subcontract to RGZ, $40,000/yr x 2 years = $80,000.
1996-1997 Deaconess Hospital BSRG Seed Grant, Co-Investigator (Dr. Osman Cay, Principal Investigator), “Videomicroscopy of liver lesions,” $10,000.
1993-1997 DOE, "Research Program in Neutron Capture Therapy at BIDMC & MIT".
Principal Investigator & Program Director, $1,550,000/yr x 5 yr = $7,750,000.
1998-2000 Supplemental funding to above grant, $165,000. Principal Investigator & Program Director.
1999-2000 IAEA, “Computational Treatment Planning Standards for NCT.” Principal
Investigator, $10,000.
2001-2002 DOE Extension Grant, "Research Program in Neutron Capture Therapy at BIDMC
& MIT,” Principal Investigator & Program Director, $1,044,616/yr x 2 yr =
$2,089,232.
2000-2001 Harvard Medical School’s Center of Excellence in Women’s Health, Women’s
Health Fund, “Proof-of-Principle of Contrast Enhanced Dual Energy
Mammography.” Co-investigator & Inventor (Dr. John Copeland Principal
Investigator), $45,000.
2000-2001 BIDMC Radiology Department Seed Grant, “Proof-of-Principle of Contrast
Enhanced Dual-Energy Mammography.” Co-Investigator & Inventor (Dr. John
Copeland Principal Investigator), $10,000.
2002-2003 DOE Extension Grant, "Research Program in Neutron Capture Therapy at BIDMC
& MIT,” Principal Investigator & Program Director, $850,000.
2001-2002 ACR-ACRIN Multi-Institutional Grant, “Evaluation of digital mammography”,
Investigator, (Dr. Janet Baum, PI), $800,000/yr x 2 yr = 1,600,000.
2001-2003 NIH R-21 grant, “BNCT of glioblastoma and intracranial melanoma”, Investigator
(Dr. Paul Busse, PI), $500,000/yr x 2 years = $1,000,000.
2002-2005 NIH RO1 grant, “BNCT of cutaneous melanoma”, Investigator (Dr. Paul Busse, PI),
$750,000/yr x 3 yr = $2,250,000. Grant terminated in 2003.
TEACHING
HARVARD BETH ISRAEL DEACONESS MEDICAL CENTER COURSES
1982-2003 Physics of Diagnostic Radiology, Nuclear Medicine, NMR, and Ultrasound. 48
h/y, Beth Israel Hospital, Harvard Medical School. 4-5, 3rd. yr. radiology
residents
1997-2003 Senior teaching faculty for Harvard Medical School Core Clerkship in Radiology.
1998-2003 Introduction to Radiological Techniques, Equipment, & Safety. 6 h/y. 6-
8 1st year radiology residents.
CONTINUING EDUCATION COURSES FOR RADIOGRAPHERS
1997-2003 Various imaging topics; 6-12 hours/annum, to meet radiographers’ CE requirements.
EXTERNAL COURSES
1979-2007 Physics of Diagnostic Radiology, Nuclear Medicine, NMR, and Ultrasound. 48
h/annum. From January 1988 – January 2001, held under the auspices of the New
England Roentgen Ray Society. 20 radiology residents & cardiology fellows.
1980-1995 Mammography: Physical Principles, Equipment Evaluation, and Quality Assurance.
8 h/year, at Tufts-NEMC, 30-35 outside radiologists (course director, Mark Homer,
MD).
TUFTS-NEMC COURSES
1980-1995 Physics of Medical Imaging, PGY 3 medical students, 12 h/y, 8-10 radiolog elective students.
2003-2007 Physics of Radiation Therapy, 1 h/week course for radiation oncology 1st–4th year
residents.
MEDICAL STUDENT COUNCELING & RESEARCH MENTORSHIP
1983 Carl Winalski (TUSM)
1984 Kay Kronberg (TUSM/Hanover Medical School, FRG)
1985 Karsden Dreinhoefer (TUSM/Hanover Medical School, FRG)
1986 Robin Aaron (TUSM)
MASTER’S & DOCTORAL STUDENT RESEARCH DISSERTATION MENTORSHIP
1974-1977 Manzar Ashtari, Ph.D., MIT
1980-1983 Ken Ulin, Ph.D., Tufts University
1985-1987 Rabia Kabani, M.S., Tufts University
1987-1988 Christiana Lui, M.S., MIT
1987-1988 Nicolas Lizzo, M.S., MIT
1989-1990 Kevin Roberts, M.S., MIT
1988-1991 Guido Solares, Ph.D., MIT
1993-1995 Gopica Yasuda, Ph.D., Tufts University
1993-1995 Chun-Shan Yam, Ph.D., MIT
1995-1995 Daniel Katz, M.S., MIT
1995-1999 Steadman Kiger, Ph.D., MIT
1996-1999 Cynthia Chuang, Ph.D., MIT
1998-2001 John Goorley, Ph.D., MIT
1996-1998 John Copeland, Ph.D., Clinical Research Fellow
1996-1998 Mark Rivard, Ph.D., Wayne State University
1998-2006 Gustavo Santa Cruz, University of Buenos Aires; Grad. Student
1998-2002 Ysushi Shibata, M.D., Ph.D., Visiting Research Fellow
2001-2003 Haejin Kang, Ph.D., Clinical Research Fellow
1999-2005 Sara Gonzalez, University of Buenos Aires (6 months); Student & IAEA Fellow
2001-2002 Fang Hsu, National University of Taiwan (6 months); Visiting Research Fellow
2004-2005 Jonathan Pioli, Ecole Superieure d’Ingenieurs de Luminy, Marseille University
LEADERSHIP ACTIVITIES
1981-1984 Co-Director, Medical Physics Residency Training Program, Radiation Oncology
Dept., Tufts-NEMC (funded by NIH)
1994-1995 Co-Director, Medical Physics Residency Training Program, Radiation Oncology
Dept., Tufts-NEMC (funded by NIH)
1997-2003 Director, Radiological Physics Fellowship/Training Program, Department of
Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School
2000-2001 Chairman, RSC Subcommittee for Auditing Operations of Radiation Safety Office
2003-2007 Vice Chairman, Department of Radiation Oncology, Tufts-New England Medical
Center
2002-2004 President, International Society for Neutron Capture Therapy Hosted biennial
congress in Boston in 2004
2007-2008 Interim Director of Medical Physics at the Midwest Proton Radiotherapy Institute
(MPRI), Bloomington, Indiana.
2002-2004 President, International Society for Neutron Capture Therapy
1998-2007 Panel Chair, Diagnostic Imaging Physics, American Board of Medical Physics
1982-1983 Chairman, NE Chapter AAPM Committee on Education (including organization of
a two-day symposium on digital angiography (with ACR CME accreditation)
1983-1984 President, New England Chapter, AAPM
BIBLIOGRAPHY (150 publications under sections 1-4 below organized as follows):
1. Scientific papers in peer-reviewed journals
2. Scientific papers in peer-reviewed proceedings
3. Technical/scientific reports & educational materials
4. Books, book chapters & monographs
5. Book reviews
6. Letters to journal editors
7. Doctoral thesis
8. Patents & copyright materials
1. SCIENTIFIC PAPERS IN PEER REVIEWED JOURNALS
1. BW Murray, GL Brownell, JA Correia, RG Zamenhof, J Harvey: "Development of an In
Vivo Neutron Activation Analysis Facility at the Massachusetts Institute of Technology,"
Trans. Am. Nucl. Soc. 18:96-98, 1974
2. RG Zamenhof, BW Murray, GL Brownell, GR Wellum, and EI Tolpin: "Boron Neutron
Capture Therapy for the Treatment for Cerebral Gliomas: I. An Evaluation of the Efficacy of
Different Neutron Beams", Med. Phys. 2:47-58, 1975
3. FC Dohan, PL Kornblith, RG Zamenhof, WH Sweet, EI Tolpin, and GR Wellum: "Boron
Neutron Capture Therapy for the Treatment of Cerebral Gliomas: II. Utilization of the
Blood-Brain Barrier and Tumor Specific Antigens for the Selective Concentration of
Boron in Gliomas", Oncology 32:223, 1975
4. MS Potsaid, R Irwin, F Castronovo, G Prout, W Harvey, A Tofe, & RG Zamenhof: "P-32
Diphosphonate Dose Determination in Cancer Patients," JNM 19:98-104, 1978
5. M Weissberger, RG Zamenhof, , S Aronow, & RM Neer: "CT Scanning for the
Measurement of Bone Mineral in the Human Spine," J. Comp. Assisted Tomog., 2:253-260,
1978
6. RG Zamenhof, M. Szulc: "A Sensitivity Evaluation of Computerized Tomography for the
Measurement of Bone Mineral in Cortical & Vertebral Bone," J. Comp. Assist. Tomog.,
3:852-353, 1979
7. RG Zamenhof: "An Interesting Form of Gamma Ray - Detector Interaction & its
Significance on Peak Centroid Determination", Med. Phys. 6:62-64, 1979
8. RG Zamenhof, OL Deutsch, and BW Murray: "Feasibility Study of Prompt Capture Gamma
In Vivo Neutron Activation Analysis", Med. Phys. 6:179-188, 1979
9. RG Zamenhof, “Nuclear activation techniques in the life sciences”, Medical Physics, 7:577,
1980
10. RG Zamenhof: "The Optimization of Signal Detectability in Digital Fluoroscopy", Med.
Phys., 5:688-696, 1982
11. MJ Homer, RG Zamenhof: "Breast Exposures Incurred by Women Undergoing an Upper GI
Series," Radiology, 145:497-501, 1982
12. RD Zwicker, RG Zamenhof, SM Wolpert: "A Dosimetric Comparison Between CT and
Polytomography for Evaluation of the Sella Tursica", A.J.N.R., 3:354-358, 1982
13. GR Wellum, RG Zamenhof, EI Tolpin: "Boron Neutron Capture Therapy for the Treatment
of Cerebral Gliomas: III: The Utilization
of Tumor-Specific Antibodies," Int. J. Rad. Oncol., Phys. Biol., 8:1339-1346, 1982
14. HD Mitcheson, RG Zamenhof, MS Bankoff, EL Prien, "Determination of the Chemical
Composition of Urinary Calculi by Computerized Tomography", J. of Urology, 130:814
820, 1983
15. K Ulin, RG Zamenhof, "The Measurement of Carbon, Nitrogen, and Oxygen in the Body
by Photon Activation Analysis," Med. Phys., 13:887-998, 1986 [recipient of the Sylvia
Sorkin- Greenfield award for "best paper in Med. Phys. in 1986”
16. K Ulin, M Meydani, RG Zamenhof, J. Blumberg, "The Effect of Protein Malnutrition
on the Carbon and Nitrogen Balance in Rats Measured by Photon Activation Analysis,"
Am. J. Clin. Nutr., 44:963-970, 1986
17. RG Zamenhof, S Shahabi, HT Morgan, "The Estimation of Exposure from Diagnostic X
ray Exams Using Standardized Exposure Functions", Am. J. Roentgenol., 149:631-638, 1987
18. RH Behrman, RG Zamenhof, and KM Blazo, "Evaluation of a Mammography Image
Enhancement System," Journal of Digital
Imaging, 2:163-170, 1989
19. RG Zamenhof, H Madoc-Jones, OK Harling, JA Bernard, "A Multidisciplinary Program
Leading to a Clinical Trial of Neutron Capture Therapy at Tufts-New England Medical
Center & the Massachusetts Institute of Technology," Strahlentherapie und Onkologie, 165:
254-256, 1989
20. RG Zamenhof, S Clement, K Lin, C Lui, D Ziegelmiller, OK Harling, "Monte Carlo
Treatment Planning and High-Resolution Alpha Track Autoradiography for Neutron Capture
Therapy," Strahlentherapie und Onkologie, 165: 188-191, 1989
21. OK Harling, SD Clement, JR Choi, JA Bernard, RG Zamenhof, "Neutron Beams for Neutron
Capture Therapy at the MIT Research Reactor," Strahlentherapie und Onkologie, 165-169:
90, 1989
22. RG Zamenhof, "The Design of Neutron Beams for Neutron Capture Therapy," Nucl. Sci.
Appl., 4:303-315, 1991
23. SC Saris, GR Solares, DE Wazer, G Cano, SE Kerley, M Joyce, LS Adelman, OK Harling, H
Madoc-Jones, RG Zamenhof, "Boron Neutron Capture Therapy of Murine Brain Tumors,"
Cancer Research, 52:4672-4677, 1992
24. OK Harling, RG Zamenhof, JC Yanch, R Choi, GR Solares, RD Rogus, DJ Moulin, L Scott
Johnson, Ilhan Olmez, S Wirdzek, JA
Bernard, CI Nwanguma, DE Wazer, S Saris, H Madoc-Jones, CB Sledge, S Shortkroff,
"Boron Neutron Capture and Radiation Synovectomy Research at the MIT Research
Reactor," Nucl. Sci. & Eng., 110:330-342, 1992
25. GR Solares, RG Zamenhof, "A New Approach to the Microdosimetry of Neutron Capture
Therapy," Trans. Am. Nucl. Soc., 65:153-157, 1992
26. J Yanch, R Zamenhof, "Dosimetry of Cf-252 Sources for Neutron Radiotherapy with and
without Augmentation by Boron Neutron Capture Therapy," Radiation Research, 131:249
255, 1992
27. R Zamenhof, D Stern, B Dawson-Hughes, "Spurious Dual-Energy X-Ray Absorptiometry
Images in a Patient Exposed to the Contrast Agent Thorotrast," Osteoporosis Int., 3:283-286,
1993
28. CS Yam, GR Solares, RG Zamenhof "Validation of the HRQAR Approach to BNCT
Microdosimetry". Trans. Am. Nucl. Soc. 71:142-144, 1994
29. K Ulin, RG Zamenhof, "The Measurement of Carbon, Nitrogen, and Oxygen in the Body by
Photon Activation Analysis," Med. Phys., 13:887-998, 1986 (recipient of the Sylvia Sorkin
Greenfield award for best paper in Med. Physics. in 1986)
30. K Ulin, M Meydani, RG Zamenhof, J. Blumberg, "The Effect of Protein Malnutrition
on the Carbon and Nitrogen Balance in Rats Measured by Photon Activation Analysis,"
Am. J. Clin. Nutr., 44:963-970, 1986
31. RG Zamenhof, S Shahabi, HT Morgan, "The Estimation of Exposure from Diagnostic X-ray
Exams Using Standardized Exposure Functions", Am. J. Roentgenol., 149:631-638, 1987
32. RH Behrman, RG Zamenhof, and KM Blazo, "Evaluation of a Mammography Image
Enhancement System," Journal of Digital Imaging, 2:163-170, 1989
33. RG Zamenhof, H Madoc-Jones, OK Harling, JA Bernard, "A Multidisciplinary Program
Leading to a Clinical Trial of Neutron Capture Therapy at Tufts-New England Medical
Center & the Massachusetts Institute of Technology," Strahlentherapie und Onkologie, 165:
254-256, 1989
34. RG Zamenhof, S Clement, K Lin, C Lui, D Ziegelmiller, OK Harling, "Monte Carlo
Treatment Planning and High-Resolution Alpha-Track Autoradiography for Neutron Capture
Therapy," Strahlentherapie und Onkologie, 165: 188-191, 1989
35. OK Harling, SD Clement, JR Choi, JA Bernard, RG Zamenhof, "Neutron Beams for Neutron
Capture Therapy at the MIT Research Reactor," Strahlentherapie und Onkologie, 165-169:
90, 1989
36. RG Zamenhof, "The Design of Neutron Beams for Neutron Capture Therapy," Nucl. Sci.
Appl., 4:303-315, 1991
37. SC Saris, GR Solares, DE Wazer, G Cano, SE Kerley, M Joyce, LS Adelman, OK Harling, H
Madoc-Jones, RG Zamenhof, "Boron Neutron Capture Therapy of Murine Brain Tumors,"
Cancer Research, 52:4672-4677, 1992
38. OK Harling, RG Zamenhof, JC Yanch, R Choi, GR Solares, RD Rogus, DJ Moulin, L Scott
Johnson, Ilhan Olmez, S Wirdzek, J Bernard, CI Nwanguma, DE Wazer, S Saris, H Madoc
Jones, CB Sledge, S Shortkroff", Boron Neutron Capture and Radiation Synovectomy
Research at the MIT Research Reactor," Nucl. Sci. & Eng., 110:330-342, 1992
39. GR Solares, RG Zamenhof, "A New Approach to the Microdosimetry of Neutron Capture
Therapy," Trans. Am. Nucl. Soc., 65:153-157, 1992
40. J Yanch, R Zamenhof, "Dosimetry of Cf-252 Sources for Neutron Radiotherapy with and
without Augmentation by Boron Neutron Capture Therapy," Radiation Research, 131:249
255, 1992
41. R Zamenhof , D Stern, , B Dawson-Hughes, "Spurious Dual-Energy X-Ray Absorptiometry
Images in a Patient Exposed to the Contrast Agent Thorotrast," Osteoporosis Int., 3:283-286,
1993
42. CS Yam, GR Solares, RG Zamenhof "Validation of the HRQAR Approach to BNCT
Microdosimetry". Trans. Am. Nucl. Soc. 71:142-144, 1994
43. OK Harling, RG Zamenhof, GR Solares, JC Yanch, DE Wazer, RD Rogus, J-M Chabeuf,
SC Yam, JA Bernard, G Cano, T DiPetrillo, H Madoc-Jones, “Preparation for Phase-I
Clinical Trials of Boron Neutron Capture Therapy at the MIT Reactor and the New
England Medical Center,” Rad. Onc. Inv., 2:109-118, 1994
44. GR Solares, RG Zamenhof, “A Novel Approach to the Microdosimetry of Neutron Capture
Therapy: Part I. High –Resolution Quantitative Autoradiography Applied to the
Microdosimetry of Neutron Capture Therapy,” Radiation Research, 144:50-58, 1995
45. GR Solares, RG Zamenhof, “A Novel Approach to the Microdosimetry of Neutron Capture
Therapy: Part I. High –Resolution Quantitative Autoradiography Applied to the
Microdosimetry of Neutron Capture Therapy,” Radiation Research, 144:50-58, 1995
46. WG Cano, RG Zamenhof, GR Solares, TA DiPetrillo, SAG Meylaerts, SC Lin, SC Saris, JF
Duker, E Goad, H Madoc-Jones, DE Wazer,
"Toxicity Associated with Boronophenylalanine and Cranial Neutron Irradiation." Rad. Onc.
Inv. 3:108-118, 1995
47. CS Yam, RG Zamenhof, GR Solares. "Microdosimetric Evaluation of Boron Compound
Efficacy". Trans. Am. Nucl. Soc. 73:26-29, 1995
48. OK Harling, RG Zamenhof, JA Bernard, H Madoc-Jones, GR Solares, CS Yam. “Initiation
of a Phase-I Trial of Neutron Capture Therapy at the MIT Research Reactor. Trans. Am.
Nucl. Soc. 73:22-23, 1995
49. RG Zamenhof, E Redmond II, GR Solares, D Katz, S Kiger, and OK Harling. “Monte Carlo
Based Treatment Planning for Boron Neutron Capture Therapy Using Custom Designed
Models Automatically Generated from CT Data.” Int. J. Rad. Oncol. Biol. Phys., 32:383-397,
1996
50. RG Zamenhof, "Microdosimetry for Boron Neutron Capture Therapy: A Review". J. of
Neuro- Oncology. 33:81-92, 1997
51. PV Prasad, P Busse, L Tang, R Zamenhof, “Proton NMR Spectroscopic Measurement of
p,Boronophenylalanine (BPA): a Preliminary Study,” Med. Phys., 26(7):1230-1234, 1999
52. C-S Yam, RG Zamenhof, “A Three-Dimensional Tumor Volume Transformation Technique
for Radiotherapy Treatment Planning," Trans. Am. Nucl. Soc. 28:91-94, 1999
53. C-S Yam, RG Zamenhof, “Computational Validation of the Stereology Principle Applied to
the Microdosimetry of Boron Neutron Capture Therapy.” Med. Phys. 27(3):549-557, 2000
54. W.S. Kiger III, M.R. Palmer, K.J. Riley, R.G. Zamenhof, and P.M. Busse, “A
Pharmacokinetic Model for the Concentration of 10B in Blood following
Boronophenylalanine-Fructose Administration in Humans,” Radiation Research,, 155:611
618, 2001
55. GA Santa Cruz, MR Palmer, E Matatagui, RG Zamenhof, “A theoretical model for event
statistics in microdosimetry; Part-I: Uniform distribution of heavy-ion tracks”, Medical
Physics, 28:1-9, 2001
56. GA Santa Cruz, MR Palmer, E Matatagui, RG Zamenhof, “A theoretical model for event
statistics in microdosimetry; part-II:
Non-uniform distribution of heavy-ion tracks”, Medical Physics, 28:1-9, 2001
57. K Hideghéty, W Sauerwein, P Busse, O Harling, R Zamenhof, A Chanana, J Coderre,
“Intercomparison of three epithermal neutron-based clinical trials of boron neutron capture
therapy”, Frontiers in Neutron Capture Therapy, 01:99-103, 2001
58. JT Goorley, WS Kiger, III, RG Zamenhof, "Reference dosimetry calculations for neutron
capture therapy with comparison of analytical and voxel models," Medical Physics, 29:145
156, 2002
59. GA Santa Cruz, MR Palmer, E Matatagui, RG Zamenhof, “A theoretical model for the
microdosimetry of discontinuous distributions of heavy particle tracks.” Radiat. Prot. Dosim.,
99:429-431, 2002
60. MR Palmer, J Tim Goorley, WS Kiger, III, PM. Busse, KJ Riley, OK Harling, RG
Zamenhof. "Treatment planning and dosimetry for the Harvard-MIT Phase I clinical trial of
cranial neutron capture therapy." Int J Radiation Oncol Biol Phys. 53(5), 1361-1379, August
2002
61. Paul M. Busse, Otto K. Harling, Matthew R. Palmer, Robert G. Zamenhof, “A critical
examination of the results from the phase I clinical trial of cranial neutron capture therapy at
Harvard-MIT: normal tissue reaction and initial tumor response”, International Journal of
Radiation Oncology, Biology, Physics, 54(2):241-242, 2002
62. JA Coderre, MJ Rivard, H Patel, RG Zamenhof, “Topics in Neutron Capture Therapy:
Proceedings of the World Congress on Neutron Capture Therapy,” Applied Radiation &
Isotopes, 61:739-743, 2004
63. MJ Rivard, RG Zamenhof, “Moderated 252Cf neutron energy spectra in brain tissue and
calculated boron neutron capture dose.” Applied Radiation & Isotopes, 61:753-757, 2004
64. FY Hsu, CJ Tung, JC Chen, YL Wang, HC Huang, RG Zamenhof, “Dose-rate scaling factor
estimation of THOR BNCT test beam.” Applied Radiation & Isotopes, 61:881-885, 2004
65. WS Kiger III, XQ Lu, OK Harling, KJ Riley, PJ Binns, J Kaplan, H Patel, RG Zamenhof, Y
Shibata, ID Kaplan, PM Busse, MR Palmer,
“Preliminary treatment planning and dosimetry for a clinical trial of neutron capture therapy
using a fission converter epithermal neutron beam.” Applied Radiation & Isotopes, 61:1075
1081, 2004
66. GA Santa Cruz, RG Zamenhof, “The Microdosimetry of the 10-B Reaction in Boron Neutron
Capture Therapy: A New Generalized Theory”. Radiation Research, 162:702-710, 2004
67. SJ Gonzalez, DG Carando, GA Santa Cruz, Robert G Zamenhof, “Voxel model in BNCT
treatment planning: performance analysis and improvements.” Phys. Med. Biol. 50:441–458,
(2005)
68. T Goorley, R Zamenhof, H Nikjoo, “Calculated DNA damage from gadolinium auger
electrons and relation to dose distributions in a head phantom.” Int. J. Radiat. Biol., 80:933
940 (2004)
69. JA Coderre, MJ Rivard, H Patel, RG Zamenhof (eds), “Topics in Neutron Capture Therapy”,
Radiation Research, 61:733-1130, 2004
70. A Wittig, J Michel, R Mossc, F Stecher-Rasmussen, HF Arlinghause, P Bendel, PL Mauri, S
Altieri, R Hilgeri, P Salvadori, L Menichetti, R Zamenhof, WAG Sauerwein, “Boron analysis
and boron imaging in biological materials for Boron Neutron Capture Therapy,” Critical
Reviews in Oncology/Hematology, 68:66–90, 2008
71. L Zhao, G. Sandison, J Farr, R Zamenhof, M Fitzek, “Measurement of Initial Respiration
Phase Effect on Simulated Lung Cancer Treatment: A Comparison between a Proton Beam
Passive Scattering Delivery System and a Uniform Scanning Delivery System,” International
Journal of Radiation Oncology Biology Physics, 72:S633–S634, 2008
2. SCIENTIFIC PAPERS IN PEER-REVIEWED PROCEEDINGS
72. RG Zamenhof, K. Ulin, "The Measurement of Carbon, Nitrogen, and Oxygen In Vivo by
Photon Activation Analysis", in: Nuclear Based Techniques for the In Vivo Study of Human
Body Composition, technical report, IAEA/RL/131, IAEA, Vienna, 1985
73. RG Zamenhof, "Optimization of Spinal Bone Density Measurement Using Computerized
Tomography," in: Osteoporosis Update 1987, ed: HK Genant, Radiology Research and
Education Foundation Press, San Francisco, 1987
74. RG Zamenhof, H Madoc-Jones, OK Harling, JA Bernard, "Neutron Capture Therapy for
Brain Tumors at New England Medical Center and the Massachusetts Institute of
Technology", in: Clinical Aspects of Neutron Capture Therapy," eds: RG Fairchild, VP
Bond, A Woodhead, Plenum Press, New York, 1988
75. H Madoc-Jones, DE Wazer, RG Zamenhof, OK Harling, JA Bernard, "Clinical
Considerations for Neutron Capture Therapy of Brain Tumors," in: Neutron Beam Design,
Development, and Performance for Neutron Capture Therapy, eds: OK Harling, JA Bernard,
RG Zamenhof, Plenum Press, New York, 1990
76. JR Choi, SD Clement, OK Harling, RG Zamenhof, "Neutron Capture Therapy Beams at the
MIT Research Reactor," in: Neutron Beam Design, Development, and Performance for
Neutron Capture Therapy, eds: OK Harling, JA Bernard, RG Zamenhof, Plenum Press, New
York, 1990
77. RG Zamenhof, SD Clement, OK Harling, JF Brenner, DE Wazer, H Madoc-Jones, JC Yanch,
"Monte Carlo Based Dosimetry and Treatment Planning for Neutron Capture Therapy," in:
Neutron Beam Design, Development, and Performance for Neutron Capture Therapy, eds:
OK Harling, JA Bernard, RG Zamenhof, Plenum Press, New York, 1990
78. SD Clement, JR Choi, RG Zamenhof, JC Yanch, OK Harling, "Monte Carlo Methods of
Neutron Beam Design for Neutron Capture Therapy at the MIT Research Reactor," in:
Neutron Beam Design, Development, and Performance for Neutron Capture Therapy,
eds: OK Harling, JA Bernard, RG Zamenhof, Plenum Press, New York, 1990
79. RG Zamenhof, J Brenner, JC Yanch, D Wazer, H Madoc-Jones, S Saris, OK Harling,
"Treatment Planning for Neutron Capture Therapy of Glioblastoma Multiforme Using an
Epithermal Neutron Beam from the MITR-II Research Reactor and Monte Carlo
Simulation," in: Progress in Neutron Capture Therapy for Cancer, eds: B Allen, D Moore, B
Harrington, New York, Plenum Press, 1992
80. G Solares, RG Zamenhof, S Saris, D Wazer, S Kerley, M Joyce, H Madoc-Jones, L
Adelman, OK Harling, "Biodistribution and Pharmacokinetics of p-Boronophenylalanine in
C57BL/6 Mice with GL261 Intracerebral Tumors, and Survival Following Neutron Capture
Therapy," in: Progress in Neutron Capture Therapy for Cancer, eds: B Allen, D Moore, B
Harrington, New York, Plenum Press, 1992
81. JR Choi, RG Zamenhof, JC Yanch, R Rogus, OK Harling, "Performance of the Currently
Available Epithermal Neutron Beam at the MIT Research Reactor," in: Progress in Neutron
Capture Therapy for Cancer, eds: B Allen, D Moore, B Harrington, New York, Plenum
Press, 1992
82. RG Zamenhof, H Madoc-Jones, OK Harling, D Wazer, S Saris, JC Yanch, G Solares, G
Rogers, "The Neutron Capture Therapy Research Program at New England Medical Center
& the Massachusetts Institute of Technology," in: Progress in Neutron Capture Therapy for
Cancer, eds: B Allen, D Moore, B Harrington, New York, Plenum Press, 1992
83. JC Yanch, RG Zamenhof, J Wierzbicki, Y Maruyama, "Comparison of Dose Distributions
with 10B Augmentation Near Linear Sources of 252Cf Obtained by Monte Carlo Simulation
& Experimental Measurement," in: Progress in Neutron Capture Therapy for Cancer, eds: B
Allen, D Moore, B Harrington, New York, Plenum Press, 1992
84. GR Solares, RG Zamenhof, G Cano, "Microdosimetry & Compound Factors for Neutron
Capture Therapy," in: Advances in Neutron Capture Therapy,” eds: R Barth, A Soloway,
Plenum Press, New York, 1993
85. RG Zamenhof, DE Wazer, J Bernard Jr., OK Harling, TA DiPetrillo, H Madoc-Jones, JA
Coderre, A Meek, "Federal & Institutional Approvals Necessary Prior to a U.S. Clinical Trial
of Neutron Capture Therapy," in: Advances in Neutron Capture Therapy, eds: R Barth, A
Soloway, Plenum Press, New York, 1993
86. GR Solares, RG Zamenhof, DE Wazer, TE DiPetrillo, SC Saris, G Cano, OK Harling, H
Madoc- Jones, "Effects of Fractionation of Boron Neutron Capture Therapy in a Mouse
Glioma Model," in: Advances in Neutron Capture Therapy,” eds: R Barth, A Soloway,
Plenum Press, New York, 1993
87. OK Harling, R Rogus, R Choi, D Moulin, J Yanch, R Zamenhof, "Dosimetry & Dose
Control for Patient BNCT Trials at the MITR-II Research Reactor," in: Topics in Dosimetry
& Treatment Planning for Neutron Capture Therapy, eds: RG Zamenhof, GR Solares, OK
Harling, Advanced Medical Publishing Inc., Madison, WI, 1994
88. G Solares, R Zamenhof, J Palano, G Cano, "Microdosimetry of Neutron Capture Therapy by
Combination of Histological and Monte Carlo Analysis," in: Topics in Dosimetry &
Treatment Planning for Neutron Capture Therapy, eds: RG Zamenhof, GR Solares, OK
Harling, Advanced Medical Publishing Inc., Madison, WI, 1994
89. Madoc-Jones, RG Zamenhof, G Solares, OK Harling, C-S Yam, K Riley, D Wazer, G
Rogers, M Atkins, “A Phase-I Dose-Escalation Trial of Boron Neutron Capture Therapy for
Subjects with Metastatic Subcutaneous Melanoma of the Extremities,” Proc. 5th. Int. Mtg. on
Prog. in RadioOncology, Salzburg, May 10-14, 1995
90. H Madoc-Jones, R Zamenhof, G Solares, O Harling, C-S Yam, K Riley, S Kiger, D Wazer,
G Rogers, M Atkins, “A Phase-I Dose Escalation Trial of Boron Neutron Capture Therapy
for Subjects with Metastatic Subcutaneous Melanoma of the Extremities,” in: Cancer
Neutron Capture Therapy, ed: Y Mishima, Plenum Press, New York, 1996
91. G Solares, S Kiger, R Zamenhof, “Microdosimetry Studies at the Harvard/MIT Phase-I
Clinical Trial of Boron Neutron Capture Therapy,” in: Advances in Neutron Capture
Therapy, eds: B Larsson, J Crawford, R Weinreich, Elsevier, Amsterdam, 1997
92. RG Zamenhof, GR Solares, WS Kiger, III, EL Redmond, PM Busse, C-S Yam,
“MacNCTPLAN: An Improved Macintosh-based Treatment Planning Program for Boron
Neutron Capture Therapy,” in: Advances in Neutron Capture Therapy, eds: B Larsson,
Crawford, R Weinreich, Elsevier, Amsterdam, 1997
93. G Solares, D Katz, O Harling, R Zamenhof, “On-line Dosimetry for Boron Neutron Capture
Therapy at the MIT Research Reactor,” in: Advances in Neutron Capture Therapy, eds: B
Larsson, J Crawford, R Weinreich, Elsevier, Amsterdam, 1997
94. PM Busse, RG Zamenhof, H Madoc-Jones, GR Solares, S Kiger, III, K Riley, C Chuang, G
Rogers, O Harling, “Clinical Follow-Up of Patients with Melanoma of the Extremity Treated
in a Phase-I Boron Neutron Capture Therapy Protocol,” in: Advances in Neutron Capture
Therapy, eds: B Larsson, J Crawford, R Weinreich, Elsevier, Amsterdam, 1997
95. DT Ingersoll, CO Slater, EL Redmond II, RG Zamenhof, “Comparison of TORT & MCNP
Dose Calculations for BNCT Treatment Planning,” in: Advances in Neutron Capture
Therapy, eds: B Larsson, J Crawford, R Weinreich, Elsevier, Amsterdam, 1997
96. PM Busse, RG Zamenhof, OK Harling, I Kaplan, J Kaplan, C Chuang, J Goorley, WS Kiger
III, K Riley, L Tang, GR Solares, M Palmer, “The Harvard-MIT BNCT Program: overview
of clinical trials and translational research.” Proceedings of the Eleventh International
Congress of Radiation Research; Dublin, U.K., pp. 702-5, 1999
97. MR Palmer, JT Goorley, WS Kiger III, PM Busse, & RG Zamenhof, “Treatment planning
and dosimetry for the Harvard-MIT phase I clinical trial for cranial BNCT.” Proceedings of
the 9th International Symposium on Neutron Capture Therapy for Cancer, Osaka, Japan,
2000
98. GA Santa Cruz, MR Palmer, WS Kiger III, E Matatagui, & R.G. Zamenhof, “A new
probabilistic approach to the microdosimetry of BNCT,” Proceedings of the 9th International
Symposium on Neutron Capture Therapy for Cancer, Osaka, Japan, October 2000
99. WS Kiger III, MR Palmer, RG Zamenhof, PM Busse. “Boron uptake by erythrocytes
following boronophenylalanine-fructose infusion in humans.” Proceedings of the 9th
International Symposium on Neutron Capture Therapy for Cancer, Osaka, Japan, October
2000
100. PM Busse, OK Harling, MR Palmer, I Kaplan, TH Newton Jr, J Kaplan, CF Chuang, WS
Kiger III, KJ Riley, JT Goorley, RG Zamenhof.
“A phase-I clinical trial for cranial bnct at Harvard-MIT.” Proceedings of the 9th
International Symposium on Neutron Capture Therapy, Osaka, Japan, October 2000
101. RG Zamenhof, H Patel, MR Palmer, O Harling, PJ Binns, KJ Riley, J Bernard, H-C Lin,
P.M. Busse, “A core laboratory for the evaluation of new boron compounds: A service to
the NCT community.” Proceedings of the 9th International Symposium on Neutron
Capture Therapy for Cancer, Osaka, Japan, October 2000
102. JF Copeland, CS Melhus, R Horton, V Venkatakrishnan, RG Zamenhof, “Practical quality
control standards for digital display monitors,” Medical Iimaging 2000: Image Display &
Visualization, ed: SK Mun, Proc. Of SPIE, vol. 3976, 2000
103. PM Busse, I Kaplan, RG Zamenhof, OK Harling, J Kaplan, CJ Chuang, JT Goorley, K
Riley, L Tang, GR Solares, MR Palmer, “Boron Neutron Capture Therapy for
Glioblastoma Multiforme & Intracranial Melanoma: Clinical Results of the Harvard-MIT
Phase-I Trial,” in: Frontiers in Neutron Capture Therapy, eds: MF Hawthorn et al, Kluwer/
Plenum Publishers, New York, 2001
104. C Zuo, PV Prasad, N Adnani, L Tang, R Zamenhof, “Spectroscopic Technique for
Measuring BPA Pharmacokinetics: a Preliminary Study,” in: Frontiers in Neutron Capture
Therapy, eds: MF Hawthorn et al, Kluwer/Plenum Publishers, New York, 2001
105. CJ Chuang PM Busse, RG Zamenhof, P Thomas, “Selective Tumor Uptake of
p,Boronophenylalanine- Fructose in an Animal Model of Hepatic Colorectal Metastases,,”
in: Frontiers in Neutron Capture Therapy, eds: MF Hawthorn et al, Kluwer/Plenum
Publishers, New York, 2001
106. PM Busse, RG Zamenhof, I Kaplan, J Kaplan, OK Harling, CJ Chuang, JT Goorley, WS
Kiger, K Riley, L Tang, GR Solares, MR Palmer, “Complete Response of Cutaneous &
Intracranial Melanoma to Boron Neutron Capture Therapy,” in: Frontiers in Neutron
Capture Therapy, eds: MF Hawthorn et al, Kluwer/Plenum Publishers, New York, 2001
107. CJ Chuang, MR Palmer, L Tang, PM Busse, RG Zamenhof, “Predicting B-10
Concentrations in Normal Brain & Glioblastoma from Blood Measurements,” in: Frontiers
in Neutron Capture Therapy, eds: MF Hawthorn et al, Kluwer/Plenum Publishers,
New York, 2001
108. CJ Chuang, MR Palmer, L Tang, PM Busse, RG Zamenhof, “Time-Dependent
Biodistribution of BPA-f in Normal & Tumor Brain Tissues in Mice,” in: Frontiers in
Neutron Capture Therapy, eds: MF Hawthorn et al, Kluwer/Plenum Publishers, New
York, 2001
109. MR Palmer, WS Kiger, C Zuo, LP Panych, CRG Guttmann, RG Zamenhof, PM Busse,
“Integrated Medical Image Registration, Patient Positioning, & Patient Monitoriong for
Cranial BNCT,” in: Frontiers in Neutron Capture Therapy, eds: MF Hawthorn et al,
Kluwer/Plenum Publishers, New York, 2001
110. T Goorley, J Capala, WS Kiger, RG Zamenhof, MR Palmer, PM Busse, F Wheeler, D
Nigg,“A Comparison of two BNCT Treatment Planning Programs: BNCT-RTPE & Mac
NCTPLAN,” in: Frontiers in Neutron Capture Therapy, eds: MF Hawthorn et al, Kluwer/
Plenum Publishers, New York, 2001
111. WS Kiger, RG Zamenhof, “Application of Realistic Microdosimetry Techniques to the
Radiobiology of BNCT,” in: Frontiers in Neutron Capture Therapy, eds: MF Hawthorn et
al, Kluwer/Plenum Publishers, New York, 2001
112. WS Kiger, KJ Riley, MR Palmer, RG Zamenhof, “A Validated Pharmacokinetic Model for
the Concentration of B-10 in Blood following BPA-f Administration in Humans,” in:
Frontiers in Neutron Capture Therapy, eds: MF Hawthorn et al, Kluwer/Plenum Publishers,
New York, 2001
113. T Goorley, WS Kiger III, RG Zamenhof, “Comparison of Snyder Head Phantom Models
Used for Neutron Capture Therapy Benchmark Monte Carlo Dosimetry Calculations,” in
Advanced Monte Carlo for Radiation Physics, Particle Transport Simulation and
Applications. Ed. A Kling, F Barao, M Nakagawa, L Tavora, P Vaz, Springer, Berlin, 2001
114. SJ Gonzalez, GA Santa Cruz, WS Kiger, JT Goorley, MR Palmer, PM Busse, RG
Zamenhof, “NCTPlan, the New PC Version of MacNCTPlan: Improvements and
Verification of a BNCT Treatment Planning System,” in: Research and Development in
Neutron Capture Therapy. Eds: W Sauerwein et al. Monduzzi Editore, Bologna, 2002
115. F-Y Hsu, MR Palmer, WS Kiger III, GA Santa Cruz, SJ Gonzalez, PM Busse, R Zamenhof,
“Comparison of Two BNCT Treatment Planning Codes: NCTPlan and MacNCTPlan,” in:
Research and Development in Neutron Capture Therapy. Eds: W Sauerwein et al.
Monduzzi Editore, Bologna, 2002
116. WS Kiger III, GA Santa Cruz, SJ Gonzalez, F-Y Hsu, KJ Riley, PJ Binns, OK Harling, MR
Palmer, PM Busse, RG Zamenhof, “Verification and Validation of the NCTPlan Treatment
Planning Program,” in: Research and Development in Neutron Capture Therapy. Eds: W
Sauerwein et al. Monduzzi Editore, Bologna, 2002
117. SJ Gonzalez, GA Santa Cruz, WS Kiger III, RG Zamenhof, “A New Computational Tool
for Constructing Dose-Volume Histograms Using Combinatorial Techniques,” in: Research
and Development in Neutron Capture Therapy. Eds: W Sauerwein et al. Monduzzi Editore,
Bologna, 2002
118. WS Kiger III, PL Micca, JA Coderre, RG Zamenhof, “Microdosimetry Analysis of the
10B(n,α)7Li Reaction for Human and Rat Neural Tissues and Tumor,” in: Research and
Development in Neutron Capture Therapy. Eds: W Sauerwein et al. Monduzzi Editore,
Bologna, 2002
119. GA Santa Cruz, RG Zamenhof, “A Theoretical Formalism to Extrapolate Measured CBE
Factors to Different Conditions of Geometry and B-10 Distribution,” in: Research and
Development in Neutron Capture Therapy. Eds: W Sauerwein et al. Monduzzi Editore,
Bologna, 2002
120. WS Kiger III, CF Chuang, MR Palmer, RG Zamenhof, PM Busse, “Pharmacokinetic
Modeling of BPA-F in Murine Glioma and Melanoma Models for NCT,” in: Research and
Development in Neutron Capture Therapy. Eds: W Sauerwein et al. Monduzzi Editore,
Bologna, 2002
121. WS Kiger, MR Palmer, KJ Riley, RG Zamenhof, PM Busse, “Pharmacokinetic Modeling
for Borobophenylalanine-Fructose Mediated Neutron Capture Therapy: B-10 Concentration
Predictions and Dosimetric Consequences,” in: Research and Development in Neutron
Capture Therapy. Eds: W Sauerwein et al. Monduzzi Editore, Bologna, 2002
122. PM Busse, OK Harling, MR Palmer, WS Kiger III J Kaplan, I Kaplan, CF Chuang, JT
Goorley, KJ Riley, TH Newton, GA Santa Cruz, X-Q Lu, RG Zamenhof, “A Critical
Examination of the Results grom the Harvard-MIT Program Phase I Clinical Trial of NCT
For Intracranial Disease,” in: Research and Development in Neutron Capture Therapy. Eds:
W Sauerwein et al. Monduzzi Editore, Bologna, 2002
123. MJ Rivard, RG Zamenhof, “Moderated Cf-252 neutron energy spectra in brain tissue and
calculated boron-neutron capture dose,” Radiation Research, 61:753-757, 2004
124. FY Hsu, CJ Tung, JC Chen, YL Wang, HC Huang, RG Zamenhof, “Dose-rate scaling factor
estimation for THOR BNCT test beam.” Radiation Research, 61:881-885, 2004
125. WS Kiger, XQ Lu, OK Harling, KJ Riley, PJ Binns, J Kaplan, H Patel, RG Zamenhof, Y
Shibata, ID Kaplan, PM Busse, MR Palmer, “Preliminary treatment planning & dosimetry
for a clinical trial of neutron capture therapy using a fission converter epithermal neutron
beam.” Radiation Research, 61:1075-1081, 2004
126. A Wittig, R Zamenhof, et al., “Boron analysis and boron imaging in biological materials for
boron neutron capture therapy”, Crit. Rev. Oncol./Hematol. (2008)
3. TECHNICAL/SCIENTIFIC REPORTS & EDUCATIONAL MATERIALS
127. RG Zamenhof, BW Murray, OL Deutsch, RI Pettigrew, RA Rydin, GL Brownell: "New
Approaches to the Dosimetry of Boron Neutron Capture Therapy at MIT and MGH," in:
Biomedical Dosimetry; IAEA SM-188, pg. 179-184, IAEA, Vienna, March, 1975
128. RG Zamenhof, MJ Homer: "Mammography: Part 1. Physical Principles," Appl. Rad., Vol.
13, No. 5, pp. 134-140, 1984
129. RG Zamenhof, MJ Homer: "Mammography: Part 2. Equipment Selection", Appl. Rad., Vol.
13, No. 6, pp. 230-234, 1984
130. JS Robertson, MJ Berger, JP Jones, KA Lathrop, JW Poston, KN Vanek, RG Zamenhof,
"The Experimental Basis for Absorbed Dose Calculations in Medical Uses of
Radionuclides", NCRP Rep. No. 83, NCRP, Bethesda, MD, 1985
131. OK Harling, JA Bernard, RG Zamenhof, H Madoc-Jones, "A Clinical Trial of Neutron
Capture Therapy for Brain Tumors," in: Utilization of Multi-Purpose Research Reactors,
IAEA SM-300, Vienna, 1988
132. RG Zamenhof, "Mammography," in: Encyclopedia of Medical Instrumentation and
Devices, John Wiley and Son, New York, 1988
133. RG Zamenhof, "Techniques for Bone Mineral Measurement," in: Radiology, Diagnosis,
Imaging, Intervention, Eds: JM Taveras, JT Ferrucci, John Wiley & Son, New York, 1988
134. OK Harling, JA Bernard, RG Zamenhof, "Critique of MIT Workshop on Neutron Beam
Design, Development, and Performance for Neutron Capture Therapy," in: Progress in
Neutron Capture Therapy for Cancer, eds: B Allen, D Moore, B Harrington, New York,
Plenum Press, 1992
135. RG Zamenhof, “Subject in Review: Health Hazards of Low-Frequency Electromagnetic
Fields,” Pediatric Alert, 21:51-54, 1993
4. BOOKS, BOOK CHAPTERS & MONOGRAPHS
136. GL Brownell, JA Correia, RG Zamenhof: "Positron Instrumentation", in: Recent Advances
in Nuclear Medicine, vol. 5, ed. JE Lawrence and TF Budinger, Grune and Stratton, New
York, 1978
137. GL Brownell, RG Zamenhof, BW Murray, and GR Wellum: "Boron Neutron Capture
Therapy", in: Therapy in Nuclear Medicine, ed. RP Spencer, Grune and Stratton, New
York, 1978
138. GR Wellum, RG Zamenhof, EI Tolpin, "An Analysis of the Possible Use of Boron Loaded
Tumor- Associated Antibodies in Boron Neutron Capture Therapy", in: Synthesis and
Applications of Isotopically Labelled Compounds, ed: WP Duncan, Elsevier, New York,
1983
139. JE Kirsch, GL Brownell, RG Zamenhof, WH Sweet, JR Messer, EP Richardson, A
Takeuchi, H Hatanaka, "Irradiation of Normal Canine Brain After Craniectomy," in:
Neutron Capture Therapy for Brain Tumors, ed: H Hatanaka, Nishimura, Japan, 1986
140. OK Harling, JA Bernard, RG Zamenhof, "Neutron Beam Design, Development, and
Performance for Neutron Capture Therapy," Plenum Press, New York, 1990
141. D Wazer, R Zamenhof, H Madoc-Jones, O Harling, "Boron Neutron Capture Therapy,"
Chapter VII in: "Radiation Oncology: Technology and Biology," eds. P Mauch and J
Loeffler, New York, Saunders, 1994
142. RG Zamenhof, GR Solares, OK Harling (eds.), “Topics in Dosimetry & Treatment Planning
for Neutron Capture Therapy, Advanced Medical Publishing Inc., Madison, WI, ISBN: 1
883526-02-7, 1994
143. RG Zamenhof, AR Bogdan. “Basic Image Formatting and Software Functions”. in:
Computed Tomography. ed: Richard H. Behrman, Clinical Communications, Inc.,
Greenwich, CT, 1995
144. RG Zamenhof, RH Behrman. “Quantitative CT,” in: Computed Tomography. ed: RH
Behrman, Clinical Communications, Inc., Greenwich, CT, 1995
145. D Wazer, R Zamenhof, H Madoc-Jones, O Harling, "Boron Neutron Capture Therapy,"
Chapter XII in: "Cancer of the Nervous System," eds: P Black and J Loeffler, Cambridge,
MA, Blackwell Science, 1996
146. R Zamenhof, PM Busse, OK Harling, T Goorley, “Boron Neutron Capture Therapy,” in:
The Modern Technology of Radiation Oncology: A Compendium for Medical Physicists
and Radiation Oncologists," ed: J VanDyk, Medical Physics Publishing, Madison, WI, 1999
147. D Rorer, A Wambersie G Whitmore, RG Zamenhof, “Current Status of Neutron Capture
Therapy,” IAEA-Tecdoc, IAEA, Vienna, 2001
148. RG Zamenhof, MR Palmer, PM Busse, “Clinical Treatment Planning for Subjects
Undergoing Boron Neutron Capture Therapy at Harvard-MIT,” in: Current Status of
Neutron Capture Therapy, Eds: D Rorer, A Wambersie G Whitmore, RG Zamenhof, IAEA
Tecdoc-1223, ISSN-1011-4289, IAEA, Vienna, 2001
149. S Green, R Zamenhof, “Radiation Measurements,” in: Practical Radiation Protection
Measurements, Ed: C Martin & D Sutton, Oxford University Press, London, U.K., 2002
150. AB Wolbarst, RG Zamenhof, W Hendee (eds), “Advances in Medical Physics” Medical
Physics Publishing, Madison, WI, 2006
5. PhD THESIS
MIT NUCLEAR ENGINEERING DEPARTMENT & HARVARD-
MIT JOINT PROGRAM IN HEALTH SCIENCE TECHNOLOGY
RG Zamenhof, "The Measurement of Total Body Elemental Composition by Prompt
Gamma Neutron Activation Analysis." Doctoral Thesis, Massachusetts Institute of
Technology, Department of Nuclear Engineering, U.S. Library of Congress No. 186233,
1977 [Supervisor: Professor Gordon L. Brownell, Dept. Nuclear Engineering, MIT]
6. BOOK REVIEWS
1. R Zamenhof, Med. Phys., 7:577, 1980
2. R Zamenhof, AJR 8:408, 1993
3. R Zamenhof, AJR 164:870, 1995
7. LETTERS TO JOURNAL EDITORS
1. R Zamenhof, "Contrast-Detail Diagrams for the Evaluation of CT Scanner Performance",
A.J.R., 135:1313, 1980
2. R Zamenhof, "Using a CT Scanner to Measure Temperature In Vivo", Med. Phys., 10:111, 1983
3. R Zamenhof, “Non-invasive thermometry with a clinical x-ray CT scanner”, Medical
Physics, 10:374, 1983
4. Y Maruyama, J Wierzbicki, M Ashtari, RJ Yaes, JL Beach, J Yanch, R Zamenhof, CB
Schroy, "Cf- 252 Neutron Capture Therapy & Teletherapy," Int. J. Rad. Onc. Biol. Phys.,
23:255, 1992
5. R Zamenhof, A Kalend, W Bloomer, "Looking for a Few Good Molecules," J. Nat. Cancer
Inst., Vol. 84, 16:1290, 1992
6. J Wierzbicki, R Zamenhof, “Comment on Monte Carlo Simulation of Cf-252 Dose
Distribution Brachytherapy,” Med. Phys. 24:8, 1997
7. R Zamenhof, comment on the recent editorial "Is there a Future for Neutron Capture
Therapy?" Int. J. Rad. Onc. Biol. Phys., 1997
8. PATENTS & COPYRIGHTS
1. RG Zamenhof, GR Solares, “High-Resolution Track-Etch Autoradiography”, U.S. Patent
#5,296,090, awarded March, 1994
2. RG Zamenhof, “Monte Carlo Based Treatment Planning for Neutron Capture Therapy”,
U.S. Patent #5,341292, awarded August, 1994
3. RG Zamenhof, RADCOMP®, a software program for diagnostic X-ray exposure
calculations, copyrighted and marketed under royalty agreement by Nuclear Associates, Inc.,
Carle Place, NY, 1984
4. RG Zamenhof, “Contrast-Enhanced Dual-Energy Subtraction Mammography”
(utility patent submitted May 16, 2018)
5. RG Zamenhof, “Deuteron therapy” (utility patent submitted February 6, 2020)
6. RG Zamenhof, Improved Iodine Contrast-Enhanced Energy Subtraction Mammography”
(utility patent submitted May 15, 2020)
9. SOFTWARE WRITTEN FOR PUBLIC DOWNLOAD
1. POLYFIT MAC
www.dropbox.com/s/n0wn4fxygxb0lia/FittingTools_MacOSX.zip?dl=0
2. POLYFIT WINDOWS
www.dropbox.com/s/x39ihoja8xp5kio/FittingTools_Win.rar?dl=0
3. POLYFIT USER’S MANUAL
www.dropbox.com/s/g3xz78082zqxwxy/PolyFit%201.1%20User%27s%20Manual.pdf?dl=0
4. RADCOMP WINDOWS
www.dropbox.com/s/e13yrpzkhype7n9/RadComp.zip?dl=0
5. RADCOMP USER’S MANUAL
www.dropbox.com/s/g3m4rk00hm809d6/RadComp4.2%20User%20Manual.pdf?dl=0
NON-ACADEMIC PUBLICATIONS
Author of bi-weekly Science Column for the Vermont Standard newspaper, 2018-2020
Author of “The Adventures of Armadillo Baby and Annabelli”, an illustrated children’s book, 2nd Ed., published by Old Johnson Place Publishing, 2018.
Author of “Seventeen Fun Science Articles”, published by Amazon Books, 2020
Author of “The Continuing Adventures of Armadillo Baby & Annabelli: In Which a Horse Teaches a Camel Dressage”, published by Amazon Books, 2022
ATTESTATION
To the best of my knowledge the facts stated in this resumé are accurate
PO Box 153
South Woodstock
VT 05071
Tel: (802) 457-5861
Fax: (802) 419-8265
Email: [email protected]
PLACE OF BIRTH
Kidugala, Tanzania, East Africa
EDUCATION
1966-1970 B.Sc. Caledonian University (U.K.) (Electrical Engineering)
1971-1972 M.Sc. University of Strathclyde (U.K.) (Bioengineering)
1973-1977 Ph.D. Massachusetts Institute of Technology (Nuclear Engineering & Applied
Radiation Physics)
POSTDOCTORAL TRAINING
1976-1978 Research Fellow in Radiological Physics, Massachusetts General Hospital, Harvard
Medical School
BOARD CERTIFICATIONS
1985 American Board of Radiology, certification in Radiological Physics
(includes three areas: therapeutic radiation physics, diagnostic radiation physics,
and nuclear medicine physics)
2015 American Portable Nuclear Gauge Association, certified user
FULL-TIME ACADEMIC APPOINTMENTS
1976-1979 Research Fellow in Physics, Harvard Medical School, Massachusetts General
Hospital
1978-1982 Assistant Professor of Radiation Oncology & Diagnostic Radiology, Tufts School of
Medicine
1982-1989 Associate Professor of Radiation Oncology and Diagnostic Radiology Tufts School
of Medicine
1989-1996 Professor of Radiology (Medical Physics), Tufts School of Medicine
1996-2004 Associate Professor of Radiology, Harvard Medical School
2003-2007 Professor of Radiation Oncology, Tufts School of Medicine
2004-2007 Vice Chairman & Director of Research, Department of Radiation Oncology, Tufts University School of Medicine
PART-TIME & VISITING ACADEMIC APPOINTMENTS
1977-1980 Adjunct Assistant Professor of Engineering, Boston University
1987-2003 Research Affiliate, Department of Nuclear Engineering, MIT
1997 Visiting Professor, Wayne State University, Department of Physics
1994-2007 Visiting Scientist, Department of Nuclear Engineering, MIT
2006 Visiting Professor, Department of Physics, University of Buenos Aires
2007-2008 Visiting Professor, Department of Physics, Indiana University
HOSPITAL & OTHER APPOINTMENTS
1979-1981 Chief, Radiotherapy Treatment Planning Section, Dept. of Radiation Oncology,
Tufts-New England Medical Center
1981-1995 Chief, Radiological Sciences Section, Dept. of Radiation Oncology, New England
Medical Center
1996-2003 Chief, Radiological Physics Section, Department of Radiology, Beth Israel
Deaconess Medical Center
2003-2007 Director, Division of Radiological Sciences, Department of Radiation Oncology,
Tufts-New England Medical Center
2004-2007 Vice Chairman & Director of Research, Department of Radiation Oncology, Tufts
School of Medicine
2007-2008 Interim Director of Proton Physics, Midwest Proton Radiotherapy Institute,
Bloomington, Indiana
2011-2013 Radiation Safety Officer, St. Francis Hospital & Medical Center, Hartford, CT
2016-2016 Director of Medical Physics, Petrone Associates, LLC, NYC, NY
AWARDS & HONORS
1971-1972 British Science Research Council Scholarship (U.K.)
1973-1975 Harvard-MIT Health Science and Technology Fellowship
1975-1977 MIT Health Sciences Fund Fellowship
1976 Sigma-Xi Research Society of North America
1987 Co-Recipient, Sylvia-Sorkin-Greenfield award for best paper in Medical Physics in 1987
2002 Elected to Fellowship of the AAPM
2011 Elected to Fellowship of the ACMP
COMMITTEE MEMBERSHIPS: REGIONAL, NATIONAL & INTERNATIONAL
1979-1982 Member of NCRP Scientific Committee-55 (Experimental Basis for Absorbed
Dose Calculations in Medical Uses of Radionuclides)
1980-1981 Member of Advisory Committee on Research, MIT Nuclear Reactor Laboratory
1981-1983 Member of American Association of Physicists in Medicine (AAPM) International
Affairs Committee
1982-1985 Member of AAPM NMR Committee
1982-1985 Member of AAPM Publications Committee
1982-1883 Member of International Atomic Energy Agency’s Advisory Panel on Nuclear
Techniques in Developing Countries
1982-1983 Chairman, NE Chapter AAPM Committee on Education (including organization of
a two-day symposium on digital angiography (with ACR CME accreditation)
1982-1985 Editor, AAPM Newsletter
1983-1984 President, New England Chapter, AAPM
1986-1987 Member, ACR Committee on Quality Assurance and Acceptance Testing of
Radiology Equipment
1986-1990 Chairman, AAPM Task Group on Bone Density Measurement
1993-1994 Member, U.S. D.O.E. Coordinating Committee for Neutron Capture Therapy
Research
1992-1995 Member of Advisory Committee for NIH Program Project Grant (Dr. Richard
Pierson PI) titled, Methods for High-Precision In Vivo Neutron Activation Analysis
for Body Composition Analysis
1990-2001 Member, Board of Councilors, International Society for Neutron Capture Therapy
1996-2014 Oral Examiner in Radiological Physics, American Board of Radiology
1997-2005 Oral Examiner in Diagnostic Physics, American College of Medical Physics
1997-1999 Associate Editor, Journal of Medical Physics
1998-2007 Panel Chairman, Diagnostic Imaging Physics, American Board of Medical Physics
1998-2005 Member, Executive Board, International Society for Neutron Capture Therapy
1998-2007 Member, Executive Board, American College of Medical Physics
2002-2004 President, International Society for Neutron Capture Therapy
2002-2005 Member, AAPM Board of Chancellors
TUFTS SCHOOL OF MEDICINE & NEW ENGLAND MEDICAL CENTER
1986-1987 Interviewer for Tufts University School of Medicine Admissions Committee
1980-1995 Volunteer Interpreter (Polish Language) for New England Medical Center, Social Services Department
1990-1991 Member of President’s Task Group on Research Goals of NEMC
1990-1991 Department of Radiation Oncology’s representative to Tufts Faculty Senate
1991-1996 Member of Department of Radiation Oncology’s Executive Committee
2003-2007 Member of NEMC’s Radiation Safety Committee
2004-2007 Member of Department of Radiation Oncology’s Executive Committee
2004-2007 Department of Radiation Oncology’s representative to Tufts Faculty Senate
HARVARD MEDICAL SCHOOL & BETH ISRAEL DEACONESS MEDICAL CENTER
1996-2003 Member of BIDMC Radiation Safety Committee
1996-2003 Member of BIDMC RSC Radiation Dosimetry Subcommittee
1996-2003 Member of BIDMC RDRC Committee
1998-2003 Member of BIDMC Committee on Clinical Investigations (IRB)
1997-2003 Member of Department of Radiology’s Grant Review & Faculty Mentorship Committee
2001-2003 Member of Department of Radiology’s Strategic Research Planning Committee
2004-2007 Member of Tufts-NEMC Radiation Safety Committee
MEMBERSHIPS IN PROFESSIONAL SOCIETIES
American Association of Physicists in Medicine - Full Member & Fellow
American College of Medical Physics - Full Member & Fellow
Biomedical Engineering Society -- Senior Member
American College of Radiology – Member, Diplomate, Oral Examiner
Institution of Electronic and Radio Engineers (U.K.) - Member
New England Roentgen Ray Society – Member and Physics Instructor in Residence
New England AAPM Chapter - Member
New England AAPM Chapter - President 1982-1983
International Society for Neutron Capture Therapy - Founding Member, President-Elect (2000-2002)
International Society for Neutron Capture Therapy - President 2002-2004
American Society for Therapeutic Radiology & Oncology – Member
Proton Therapy Combined Oncology Group - Member
PRESENT & PAST RESEARCH INTERESTS
Neutron Capture Therapy: micro-dosimetry, treatment planning, nuclear assay, epithermal beam development, animal & human studies, research program management. This has been my main research activity throughout a large part of my academic career.
CT-based bone density measurement techniques: development, implementation, and optimization (co-inventor of QCT, early researcher on dual-energy CT applications).
Development of dual-energy digital mammography using a molybdenum contrast agent (inventor). Patent applied for.
Development of dual-energy digital mammography using iodine as a contrast agent and X-ray spectra produced by tellurium and cerium (inventor). Patent applied for.
Algorithms for monitoring of individual patient exposures from x-ray procedures. RadComp, an x-ray radiation dose application (inventor).
The deuteron as a proton-complementary particle for treatment of eye tumors and other shallow tumors where targeting precision is critical (inventor). Patent applied for.
RESEARCH UNDER FEDERAL & PRIVATE GRANT SUPPORT
[Over $20,000,000 in grants & contracts awarded between 1982 & 2003 as a principal investigator]
1982-1983 USDA "Measurement of Body Elemental Composition by Photon Activation Analysis", Principal Investigator, $20,000.
1985-1986 Siemens Corporation "Development of Software for the DR3 CT Scanner for automatic analysis of bone density scans”. Principal Investigator, $20,000.
1987-1990 DOE "Preclinical and Clinical Investigations of Neutron Capture Therapy", Principal Investigator & Program Director, $600,000 x3 = $1,800,000.
1990-1993 DOE "Renewal Grant for NEMC-MIT Preclinical Program in Neutron Capture Therapy", Principal Investigator & Program Director, $1,100,000 x3 = $3,300,000.
1991-1992 DOE "Conference Grant to Support an International Workshop in Macro- and Micro-Dosimetry & Treatment Planning”. Principal Investigator, $40,000.
1993-1995 Herbert M. Karol Cancer Foundation "Microdistribution & Microdosimetry of Boron Compounds for Use in Boron Neutron Capture Therapy of Brain Tumors", Principal Investigator, $20,000.
1993-1996 DOE 1 year Grant Extension for NEMC-MIT Preclinical Program in Neutron Capture Therapy", Principal Investigator & Program Director, $1,100,000.
1994-1998 DOE "Continuation of Research Program in Neutron Capture Therapy at NEMC & MIT", Principal Investigator & Program Director, $1,100,000 x3 = $3,300,000.
1996-1998 DOE "Acceleration of the MCNP Los Alamos Monte Carlo Code for Use in Treatment Planning for Boron Neutron Capture Therapy", Investigator (Dr. Guy Estes, LANL, Principal Investigator), subcontract to RGZ, $40,000/yr x 2 years = $80,000.
1996-1997 Deaconess Hospital BSRG Seed Grant, Co-Investigator (Dr. Osman Cay, Principal Investigator), “Videomicroscopy of liver lesions,” $10,000.
1993-1997 DOE, "Research Program in Neutron Capture Therapy at BIDMC & MIT".
Principal Investigator & Program Director, $1,550,000/yr x 5 yr = $7,750,000.
1998-2000 Supplemental funding to above grant, $165,000. Principal Investigator & Program Director.
1999-2000 IAEA, “Computational Treatment Planning Standards for NCT.” Principal
Investigator, $10,000.
2001-2002 DOE Extension Grant, "Research Program in Neutron Capture Therapy at BIDMC
& MIT,” Principal Investigator & Program Director, $1,044,616/yr x 2 yr =
$2,089,232.
2000-2001 Harvard Medical School’s Center of Excellence in Women’s Health, Women’s
Health Fund, “Proof-of-Principle of Contrast Enhanced Dual Energy
Mammography.” Co-investigator & Inventor (Dr. John Copeland Principal
Investigator), $45,000.
2000-2001 BIDMC Radiology Department Seed Grant, “Proof-of-Principle of Contrast
Enhanced Dual-Energy Mammography.” Co-Investigator & Inventor (Dr. John
Copeland Principal Investigator), $10,000.
2002-2003 DOE Extension Grant, "Research Program in Neutron Capture Therapy at BIDMC
& MIT,” Principal Investigator & Program Director, $850,000.
2001-2002 ACR-ACRIN Multi-Institutional Grant, “Evaluation of digital mammography”,
Investigator, (Dr. Janet Baum, PI), $800,000/yr x 2 yr = 1,600,000.
2001-2003 NIH R-21 grant, “BNCT of glioblastoma and intracranial melanoma”, Investigator
(Dr. Paul Busse, PI), $500,000/yr x 2 years = $1,000,000.
2002-2005 NIH RO1 grant, “BNCT of cutaneous melanoma”, Investigator (Dr. Paul Busse, PI),
$750,000/yr x 3 yr = $2,250,000. Grant terminated in 2003.
TEACHING
HARVARD BETH ISRAEL DEACONESS MEDICAL CENTER COURSES
1982-2003 Physics of Diagnostic Radiology, Nuclear Medicine, NMR, and Ultrasound. 48
h/y, Beth Israel Hospital, Harvard Medical School. 4-5, 3rd. yr. radiology
residents
1997-2003 Senior teaching faculty for Harvard Medical School Core Clerkship in Radiology.
1998-2003 Introduction to Radiological Techniques, Equipment, & Safety. 6 h/y. 6-
8 1st year radiology residents.
CONTINUING EDUCATION COURSES FOR RADIOGRAPHERS
1997-2003 Various imaging topics; 6-12 hours/annum, to meet radiographers’ CE requirements.
EXTERNAL COURSES
1979-2007 Physics of Diagnostic Radiology, Nuclear Medicine, NMR, and Ultrasound. 48
h/annum. From January 1988 – January 2001, held under the auspices of the New
England Roentgen Ray Society. 20 radiology residents & cardiology fellows.
1980-1995 Mammography: Physical Principles, Equipment Evaluation, and Quality Assurance.
8 h/year, at Tufts-NEMC, 30-35 outside radiologists (course director, Mark Homer,
MD).
TUFTS-NEMC COURSES
1980-1995 Physics of Medical Imaging, PGY 3 medical students, 12 h/y, 8-10 radiolog elective students.
2003-2007 Physics of Radiation Therapy, 1 h/week course for radiation oncology 1st–4th year
residents.
MEDICAL STUDENT COUNCELING & RESEARCH MENTORSHIP
1983 Carl Winalski (TUSM)
1984 Kay Kronberg (TUSM/Hanover Medical School, FRG)
1985 Karsden Dreinhoefer (TUSM/Hanover Medical School, FRG)
1986 Robin Aaron (TUSM)
MASTER’S & DOCTORAL STUDENT RESEARCH DISSERTATION MENTORSHIP
1974-1977 Manzar Ashtari, Ph.D., MIT
1980-1983 Ken Ulin, Ph.D., Tufts University
1985-1987 Rabia Kabani, M.S., Tufts University
1987-1988 Christiana Lui, M.S., MIT
1987-1988 Nicolas Lizzo, M.S., MIT
1989-1990 Kevin Roberts, M.S., MIT
1988-1991 Guido Solares, Ph.D., MIT
1993-1995 Gopica Yasuda, Ph.D., Tufts University
1993-1995 Chun-Shan Yam, Ph.D., MIT
1995-1995 Daniel Katz, M.S., MIT
1995-1999 Steadman Kiger, Ph.D., MIT
1996-1999 Cynthia Chuang, Ph.D., MIT
1998-2001 John Goorley, Ph.D., MIT
1996-1998 John Copeland, Ph.D., Clinical Research Fellow
1996-1998 Mark Rivard, Ph.D., Wayne State University
1998-2006 Gustavo Santa Cruz, University of Buenos Aires; Grad. Student
1998-2002 Ysushi Shibata, M.D., Ph.D., Visiting Research Fellow
2001-2003 Haejin Kang, Ph.D., Clinical Research Fellow
1999-2005 Sara Gonzalez, University of Buenos Aires (6 months); Student & IAEA Fellow
2001-2002 Fang Hsu, National University of Taiwan (6 months); Visiting Research Fellow
2004-2005 Jonathan Pioli, Ecole Superieure d’Ingenieurs de Luminy, Marseille University
LEADERSHIP ACTIVITIES
1981-1984 Co-Director, Medical Physics Residency Training Program, Radiation Oncology
Dept., Tufts-NEMC (funded by NIH)
1994-1995 Co-Director, Medical Physics Residency Training Program, Radiation Oncology
Dept., Tufts-NEMC (funded by NIH)
1997-2003 Director, Radiological Physics Fellowship/Training Program, Department of
Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School
2000-2001 Chairman, RSC Subcommittee for Auditing Operations of Radiation Safety Office
2003-2007 Vice Chairman, Department of Radiation Oncology, Tufts-New England Medical
Center
2002-2004 President, International Society for Neutron Capture Therapy Hosted biennial
congress in Boston in 2004
2007-2008 Interim Director of Medical Physics at the Midwest Proton Radiotherapy Institute
(MPRI), Bloomington, Indiana.
2002-2004 President, International Society for Neutron Capture Therapy
1998-2007 Panel Chair, Diagnostic Imaging Physics, American Board of Medical Physics
1982-1983 Chairman, NE Chapter AAPM Committee on Education (including organization of
a two-day symposium on digital angiography (with ACR CME accreditation)
1983-1984 President, New England Chapter, AAPM
BIBLIOGRAPHY (150 publications under sections 1-4 below organized as follows):
1. Scientific papers in peer-reviewed journals
2. Scientific papers in peer-reviewed proceedings
3. Technical/scientific reports & educational materials
4. Books, book chapters & monographs
5. Book reviews
6. Letters to journal editors
7. Doctoral thesis
8. Patents & copyright materials
1. SCIENTIFIC PAPERS IN PEER REVIEWED JOURNALS
1. BW Murray, GL Brownell, JA Correia, RG Zamenhof, J Harvey: "Development of an In
Vivo Neutron Activation Analysis Facility at the Massachusetts Institute of Technology,"
Trans. Am. Nucl. Soc. 18:96-98, 1974
2. RG Zamenhof, BW Murray, GL Brownell, GR Wellum, and EI Tolpin: "Boron Neutron
Capture Therapy for the Treatment for Cerebral Gliomas: I. An Evaluation of the Efficacy of
Different Neutron Beams", Med. Phys. 2:47-58, 1975
3. FC Dohan, PL Kornblith, RG Zamenhof, WH Sweet, EI Tolpin, and GR Wellum: "Boron
Neutron Capture Therapy for the Treatment of Cerebral Gliomas: II. Utilization of the
Blood-Brain Barrier and Tumor Specific Antigens for the Selective Concentration of
Boron in Gliomas", Oncology 32:223, 1975
4. MS Potsaid, R Irwin, F Castronovo, G Prout, W Harvey, A Tofe, & RG Zamenhof: "P-32
Diphosphonate Dose Determination in Cancer Patients," JNM 19:98-104, 1978
5. M Weissberger, RG Zamenhof, , S Aronow, & RM Neer: "CT Scanning for the
Measurement of Bone Mineral in the Human Spine," J. Comp. Assisted Tomog., 2:253-260,
1978
6. RG Zamenhof, M. Szulc: "A Sensitivity Evaluation of Computerized Tomography for the
Measurement of Bone Mineral in Cortical & Vertebral Bone," J. Comp. Assist. Tomog.,
3:852-353, 1979
7. RG Zamenhof: "An Interesting Form of Gamma Ray - Detector Interaction & its
Significance on Peak Centroid Determination", Med. Phys. 6:62-64, 1979
8. RG Zamenhof, OL Deutsch, and BW Murray: "Feasibility Study of Prompt Capture Gamma
In Vivo Neutron Activation Analysis", Med. Phys. 6:179-188, 1979
9. RG Zamenhof, “Nuclear activation techniques in the life sciences”, Medical Physics, 7:577,
1980
10. RG Zamenhof: "The Optimization of Signal Detectability in Digital Fluoroscopy", Med.
Phys., 5:688-696, 1982
11. MJ Homer, RG Zamenhof: "Breast Exposures Incurred by Women Undergoing an Upper GI
Series," Radiology, 145:497-501, 1982
12. RD Zwicker, RG Zamenhof, SM Wolpert: "A Dosimetric Comparison Between CT and
Polytomography for Evaluation of the Sella Tursica", A.J.N.R., 3:354-358, 1982
13. GR Wellum, RG Zamenhof, EI Tolpin: "Boron Neutron Capture Therapy for the Treatment
of Cerebral Gliomas: III: The Utilization
of Tumor-Specific Antibodies," Int. J. Rad. Oncol., Phys. Biol., 8:1339-1346, 1982
14. HD Mitcheson, RG Zamenhof, MS Bankoff, EL Prien, "Determination of the Chemical
Composition of Urinary Calculi by Computerized Tomography", J. of Urology, 130:814
820, 1983
15. K Ulin, RG Zamenhof, "The Measurement of Carbon, Nitrogen, and Oxygen in the Body
by Photon Activation Analysis," Med. Phys., 13:887-998, 1986 [recipient of the Sylvia
Sorkin- Greenfield award for "best paper in Med. Phys. in 1986”
16. K Ulin, M Meydani, RG Zamenhof, J. Blumberg, "The Effect of Protein Malnutrition
on the Carbon and Nitrogen Balance in Rats Measured by Photon Activation Analysis,"
Am. J. Clin. Nutr., 44:963-970, 1986
17. RG Zamenhof, S Shahabi, HT Morgan, "The Estimation of Exposure from Diagnostic X
ray Exams Using Standardized Exposure Functions", Am. J. Roentgenol., 149:631-638, 1987
18. RH Behrman, RG Zamenhof, and KM Blazo, "Evaluation of a Mammography Image
Enhancement System," Journal of Digital
Imaging, 2:163-170, 1989
19. RG Zamenhof, H Madoc-Jones, OK Harling, JA Bernard, "A Multidisciplinary Program
Leading to a Clinical Trial of Neutron Capture Therapy at Tufts-New England Medical
Center & the Massachusetts Institute of Technology," Strahlentherapie und Onkologie, 165:
254-256, 1989
20. RG Zamenhof, S Clement, K Lin, C Lui, D Ziegelmiller, OK Harling, "Monte Carlo
Treatment Planning and High-Resolution Alpha Track Autoradiography for Neutron Capture
Therapy," Strahlentherapie und Onkologie, 165: 188-191, 1989
21. OK Harling, SD Clement, JR Choi, JA Bernard, RG Zamenhof, "Neutron Beams for Neutron
Capture Therapy at the MIT Research Reactor," Strahlentherapie und Onkologie, 165-169:
90, 1989
22. RG Zamenhof, "The Design of Neutron Beams for Neutron Capture Therapy," Nucl. Sci.
Appl., 4:303-315, 1991
23. SC Saris, GR Solares, DE Wazer, G Cano, SE Kerley, M Joyce, LS Adelman, OK Harling, H
Madoc-Jones, RG Zamenhof, "Boron Neutron Capture Therapy of Murine Brain Tumors,"
Cancer Research, 52:4672-4677, 1992
24. OK Harling, RG Zamenhof, JC Yanch, R Choi, GR Solares, RD Rogus, DJ Moulin, L Scott
Johnson, Ilhan Olmez, S Wirdzek, JA
Bernard, CI Nwanguma, DE Wazer, S Saris, H Madoc-Jones, CB Sledge, S Shortkroff,
"Boron Neutron Capture and Radiation Synovectomy Research at the MIT Research
Reactor," Nucl. Sci. & Eng., 110:330-342, 1992
25. GR Solares, RG Zamenhof, "A New Approach to the Microdosimetry of Neutron Capture
Therapy," Trans. Am. Nucl. Soc., 65:153-157, 1992
26. J Yanch, R Zamenhof, "Dosimetry of Cf-252 Sources for Neutron Radiotherapy with and
without Augmentation by Boron Neutron Capture Therapy," Radiation Research, 131:249
255, 1992
27. R Zamenhof, D Stern, B Dawson-Hughes, "Spurious Dual-Energy X-Ray Absorptiometry
Images in a Patient Exposed to the Contrast Agent Thorotrast," Osteoporosis Int., 3:283-286,
1993
28. CS Yam, GR Solares, RG Zamenhof "Validation of the HRQAR Approach to BNCT
Microdosimetry". Trans. Am. Nucl. Soc. 71:142-144, 1994
29. K Ulin, RG Zamenhof, "The Measurement of Carbon, Nitrogen, and Oxygen in the Body by
Photon Activation Analysis," Med. Phys., 13:887-998, 1986 (recipient of the Sylvia Sorkin
Greenfield award for best paper in Med. Physics. in 1986)
30. K Ulin, M Meydani, RG Zamenhof, J. Blumberg, "The Effect of Protein Malnutrition
on the Carbon and Nitrogen Balance in Rats Measured by Photon Activation Analysis,"
Am. J. Clin. Nutr., 44:963-970, 1986
31. RG Zamenhof, S Shahabi, HT Morgan, "The Estimation of Exposure from Diagnostic X-ray
Exams Using Standardized Exposure Functions", Am. J. Roentgenol., 149:631-638, 1987
32. RH Behrman, RG Zamenhof, and KM Blazo, "Evaluation of a Mammography Image
Enhancement System," Journal of Digital Imaging, 2:163-170, 1989
33. RG Zamenhof, H Madoc-Jones, OK Harling, JA Bernard, "A Multidisciplinary Program
Leading to a Clinical Trial of Neutron Capture Therapy at Tufts-New England Medical
Center & the Massachusetts Institute of Technology," Strahlentherapie und Onkologie, 165:
254-256, 1989
34. RG Zamenhof, S Clement, K Lin, C Lui, D Ziegelmiller, OK Harling, "Monte Carlo
Treatment Planning and High-Resolution Alpha-Track Autoradiography for Neutron Capture
Therapy," Strahlentherapie und Onkologie, 165: 188-191, 1989
35. OK Harling, SD Clement, JR Choi, JA Bernard, RG Zamenhof, "Neutron Beams for Neutron
Capture Therapy at the MIT Research Reactor," Strahlentherapie und Onkologie, 165-169:
90, 1989
36. RG Zamenhof, "The Design of Neutron Beams for Neutron Capture Therapy," Nucl. Sci.
Appl., 4:303-315, 1991
37. SC Saris, GR Solares, DE Wazer, G Cano, SE Kerley, M Joyce, LS Adelman, OK Harling, H
Madoc-Jones, RG Zamenhof, "Boron Neutron Capture Therapy of Murine Brain Tumors,"
Cancer Research, 52:4672-4677, 1992
38. OK Harling, RG Zamenhof, JC Yanch, R Choi, GR Solares, RD Rogus, DJ Moulin, L Scott
Johnson, Ilhan Olmez, S Wirdzek, J Bernard, CI Nwanguma, DE Wazer, S Saris, H Madoc
Jones, CB Sledge, S Shortkroff", Boron Neutron Capture and Radiation Synovectomy
Research at the MIT Research Reactor," Nucl. Sci. & Eng., 110:330-342, 1992
39. GR Solares, RG Zamenhof, "A New Approach to the Microdosimetry of Neutron Capture
Therapy," Trans. Am. Nucl. Soc., 65:153-157, 1992
40. J Yanch, R Zamenhof, "Dosimetry of Cf-252 Sources for Neutron Radiotherapy with and
without Augmentation by Boron Neutron Capture Therapy," Radiation Research, 131:249
255, 1992
41. R Zamenhof , D Stern, , B Dawson-Hughes, "Spurious Dual-Energy X-Ray Absorptiometry
Images in a Patient Exposed to the Contrast Agent Thorotrast," Osteoporosis Int., 3:283-286,
1993
42. CS Yam, GR Solares, RG Zamenhof "Validation of the HRQAR Approach to BNCT
Microdosimetry". Trans. Am. Nucl. Soc. 71:142-144, 1994
43. OK Harling, RG Zamenhof, GR Solares, JC Yanch, DE Wazer, RD Rogus, J-M Chabeuf,
SC Yam, JA Bernard, G Cano, T DiPetrillo, H Madoc-Jones, “Preparation for Phase-I
Clinical Trials of Boron Neutron Capture Therapy at the MIT Reactor and the New
England Medical Center,” Rad. Onc. Inv., 2:109-118, 1994
44. GR Solares, RG Zamenhof, “A Novel Approach to the Microdosimetry of Neutron Capture
Therapy: Part I. High –Resolution Quantitative Autoradiography Applied to the
Microdosimetry of Neutron Capture Therapy,” Radiation Research, 144:50-58, 1995
45. GR Solares, RG Zamenhof, “A Novel Approach to the Microdosimetry of Neutron Capture
Therapy: Part I. High –Resolution Quantitative Autoradiography Applied to the
Microdosimetry of Neutron Capture Therapy,” Radiation Research, 144:50-58, 1995
46. WG Cano, RG Zamenhof, GR Solares, TA DiPetrillo, SAG Meylaerts, SC Lin, SC Saris, JF
Duker, E Goad, H Madoc-Jones, DE Wazer,
"Toxicity Associated with Boronophenylalanine and Cranial Neutron Irradiation." Rad. Onc.
Inv. 3:108-118, 1995
47. CS Yam, RG Zamenhof, GR Solares. "Microdosimetric Evaluation of Boron Compound
Efficacy". Trans. Am. Nucl. Soc. 73:26-29, 1995
48. OK Harling, RG Zamenhof, JA Bernard, H Madoc-Jones, GR Solares, CS Yam. “Initiation
of a Phase-I Trial of Neutron Capture Therapy at the MIT Research Reactor. Trans. Am.
Nucl. Soc. 73:22-23, 1995
49. RG Zamenhof, E Redmond II, GR Solares, D Katz, S Kiger, and OK Harling. “Monte Carlo
Based Treatment Planning for Boron Neutron Capture Therapy Using Custom Designed
Models Automatically Generated from CT Data.” Int. J. Rad. Oncol. Biol. Phys., 32:383-397,
1996
50. RG Zamenhof, "Microdosimetry for Boron Neutron Capture Therapy: A Review". J. of
Neuro- Oncology. 33:81-92, 1997
51. PV Prasad, P Busse, L Tang, R Zamenhof, “Proton NMR Spectroscopic Measurement of
p,Boronophenylalanine (BPA): a Preliminary Study,” Med. Phys., 26(7):1230-1234, 1999
52. C-S Yam, RG Zamenhof, “A Three-Dimensional Tumor Volume Transformation Technique
for Radiotherapy Treatment Planning," Trans. Am. Nucl. Soc. 28:91-94, 1999
53. C-S Yam, RG Zamenhof, “Computational Validation of the Stereology Principle Applied to
the Microdosimetry of Boron Neutron Capture Therapy.” Med. Phys. 27(3):549-557, 2000
54. W.S. Kiger III, M.R. Palmer, K.J. Riley, R.G. Zamenhof, and P.M. Busse, “A
Pharmacokinetic Model for the Concentration of 10B in Blood following
Boronophenylalanine-Fructose Administration in Humans,” Radiation Research,, 155:611
618, 2001
55. GA Santa Cruz, MR Palmer, E Matatagui, RG Zamenhof, “A theoretical model for event
statistics in microdosimetry; Part-I: Uniform distribution of heavy-ion tracks”, Medical
Physics, 28:1-9, 2001
56. GA Santa Cruz, MR Palmer, E Matatagui, RG Zamenhof, “A theoretical model for event
statistics in microdosimetry; part-II:
Non-uniform distribution of heavy-ion tracks”, Medical Physics, 28:1-9, 2001
57. K Hideghéty, W Sauerwein, P Busse, O Harling, R Zamenhof, A Chanana, J Coderre,
“Intercomparison of three epithermal neutron-based clinical trials of boron neutron capture
therapy”, Frontiers in Neutron Capture Therapy, 01:99-103, 2001
58. JT Goorley, WS Kiger, III, RG Zamenhof, "Reference dosimetry calculations for neutron
capture therapy with comparison of analytical and voxel models," Medical Physics, 29:145
156, 2002
59. GA Santa Cruz, MR Palmer, E Matatagui, RG Zamenhof, “A theoretical model for the
microdosimetry of discontinuous distributions of heavy particle tracks.” Radiat. Prot. Dosim.,
99:429-431, 2002
60. MR Palmer, J Tim Goorley, WS Kiger, III, PM. Busse, KJ Riley, OK Harling, RG
Zamenhof. "Treatment planning and dosimetry for the Harvard-MIT Phase I clinical trial of
cranial neutron capture therapy." Int J Radiation Oncol Biol Phys. 53(5), 1361-1379, August
2002
61. Paul M. Busse, Otto K. Harling, Matthew R. Palmer, Robert G. Zamenhof, “A critical
examination of the results from the phase I clinical trial of cranial neutron capture therapy at
Harvard-MIT: normal tissue reaction and initial tumor response”, International Journal of
Radiation Oncology, Biology, Physics, 54(2):241-242, 2002
62. JA Coderre, MJ Rivard, H Patel, RG Zamenhof, “Topics in Neutron Capture Therapy:
Proceedings of the World Congress on Neutron Capture Therapy,” Applied Radiation &
Isotopes, 61:739-743, 2004
63. MJ Rivard, RG Zamenhof, “Moderated 252Cf neutron energy spectra in brain tissue and
calculated boron neutron capture dose.” Applied Radiation & Isotopes, 61:753-757, 2004
64. FY Hsu, CJ Tung, JC Chen, YL Wang, HC Huang, RG Zamenhof, “Dose-rate scaling factor
estimation of THOR BNCT test beam.” Applied Radiation & Isotopes, 61:881-885, 2004
65. WS Kiger III, XQ Lu, OK Harling, KJ Riley, PJ Binns, J Kaplan, H Patel, RG Zamenhof, Y
Shibata, ID Kaplan, PM Busse, MR Palmer,
“Preliminary treatment planning and dosimetry for a clinical trial of neutron capture therapy
using a fission converter epithermal neutron beam.” Applied Radiation & Isotopes, 61:1075
1081, 2004
66. GA Santa Cruz, RG Zamenhof, “The Microdosimetry of the 10-B Reaction in Boron Neutron
Capture Therapy: A New Generalized Theory”. Radiation Research, 162:702-710, 2004
67. SJ Gonzalez, DG Carando, GA Santa Cruz, Robert G Zamenhof, “Voxel model in BNCT
treatment planning: performance analysis and improvements.” Phys. Med. Biol. 50:441–458,
(2005)
68. T Goorley, R Zamenhof, H Nikjoo, “Calculated DNA damage from gadolinium auger
electrons and relation to dose distributions in a head phantom.” Int. J. Radiat. Biol., 80:933
940 (2004)
69. JA Coderre, MJ Rivard, H Patel, RG Zamenhof (eds), “Topics in Neutron Capture Therapy”,
Radiation Research, 61:733-1130, 2004
70. A Wittig, J Michel, R Mossc, F Stecher-Rasmussen, HF Arlinghause, P Bendel, PL Mauri, S
Altieri, R Hilgeri, P Salvadori, L Menichetti, R Zamenhof, WAG Sauerwein, “Boron analysis
and boron imaging in biological materials for Boron Neutron Capture Therapy,” Critical
Reviews in Oncology/Hematology, 68:66–90, 2008
71. L Zhao, G. Sandison, J Farr, R Zamenhof, M Fitzek, “Measurement of Initial Respiration
Phase Effect on Simulated Lung Cancer Treatment: A Comparison between a Proton Beam
Passive Scattering Delivery System and a Uniform Scanning Delivery System,” International
Journal of Radiation Oncology Biology Physics, 72:S633–S634, 2008
2. SCIENTIFIC PAPERS IN PEER-REVIEWED PROCEEDINGS
72. RG Zamenhof, K. Ulin, "The Measurement of Carbon, Nitrogen, and Oxygen In Vivo by
Photon Activation Analysis", in: Nuclear Based Techniques for the In Vivo Study of Human
Body Composition, technical report, IAEA/RL/131, IAEA, Vienna, 1985
73. RG Zamenhof, "Optimization of Spinal Bone Density Measurement Using Computerized
Tomography," in: Osteoporosis Update 1987, ed: HK Genant, Radiology Research and
Education Foundation Press, San Francisco, 1987
74. RG Zamenhof, H Madoc-Jones, OK Harling, JA Bernard, "Neutron Capture Therapy for
Brain Tumors at New England Medical Center and the Massachusetts Institute of
Technology", in: Clinical Aspects of Neutron Capture Therapy," eds: RG Fairchild, VP
Bond, A Woodhead, Plenum Press, New York, 1988
75. H Madoc-Jones, DE Wazer, RG Zamenhof, OK Harling, JA Bernard, "Clinical
Considerations for Neutron Capture Therapy of Brain Tumors," in: Neutron Beam Design,
Development, and Performance for Neutron Capture Therapy, eds: OK Harling, JA Bernard,
RG Zamenhof, Plenum Press, New York, 1990
76. JR Choi, SD Clement, OK Harling, RG Zamenhof, "Neutron Capture Therapy Beams at the
MIT Research Reactor," in: Neutron Beam Design, Development, and Performance for
Neutron Capture Therapy, eds: OK Harling, JA Bernard, RG Zamenhof, Plenum Press, New
York, 1990
77. RG Zamenhof, SD Clement, OK Harling, JF Brenner, DE Wazer, H Madoc-Jones, JC Yanch,
"Monte Carlo Based Dosimetry and Treatment Planning for Neutron Capture Therapy," in:
Neutron Beam Design, Development, and Performance for Neutron Capture Therapy, eds:
OK Harling, JA Bernard, RG Zamenhof, Plenum Press, New York, 1990
78. SD Clement, JR Choi, RG Zamenhof, JC Yanch, OK Harling, "Monte Carlo Methods of
Neutron Beam Design for Neutron Capture Therapy at the MIT Research Reactor," in:
Neutron Beam Design, Development, and Performance for Neutron Capture Therapy,
eds: OK Harling, JA Bernard, RG Zamenhof, Plenum Press, New York, 1990
79. RG Zamenhof, J Brenner, JC Yanch, D Wazer, H Madoc-Jones, S Saris, OK Harling,
"Treatment Planning for Neutron Capture Therapy of Glioblastoma Multiforme Using an
Epithermal Neutron Beam from the MITR-II Research Reactor and Monte Carlo
Simulation," in: Progress in Neutron Capture Therapy for Cancer, eds: B Allen, D Moore, B
Harrington, New York, Plenum Press, 1992
80. G Solares, RG Zamenhof, S Saris, D Wazer, S Kerley, M Joyce, H Madoc-Jones, L
Adelman, OK Harling, "Biodistribution and Pharmacokinetics of p-Boronophenylalanine in
C57BL/6 Mice with GL261 Intracerebral Tumors, and Survival Following Neutron Capture
Therapy," in: Progress in Neutron Capture Therapy for Cancer, eds: B Allen, D Moore, B
Harrington, New York, Plenum Press, 1992
81. JR Choi, RG Zamenhof, JC Yanch, R Rogus, OK Harling, "Performance of the Currently
Available Epithermal Neutron Beam at the MIT Research Reactor," in: Progress in Neutron
Capture Therapy for Cancer, eds: B Allen, D Moore, B Harrington, New York, Plenum
Press, 1992
82. RG Zamenhof, H Madoc-Jones, OK Harling, D Wazer, S Saris, JC Yanch, G Solares, G
Rogers, "The Neutron Capture Therapy Research Program at New England Medical Center
& the Massachusetts Institute of Technology," in: Progress in Neutron Capture Therapy for
Cancer, eds: B Allen, D Moore, B Harrington, New York, Plenum Press, 1992
83. JC Yanch, RG Zamenhof, J Wierzbicki, Y Maruyama, "Comparison of Dose Distributions
with 10B Augmentation Near Linear Sources of 252Cf Obtained by Monte Carlo Simulation
& Experimental Measurement," in: Progress in Neutron Capture Therapy for Cancer, eds: B
Allen, D Moore, B Harrington, New York, Plenum Press, 1992
84. GR Solares, RG Zamenhof, G Cano, "Microdosimetry & Compound Factors for Neutron
Capture Therapy," in: Advances in Neutron Capture Therapy,” eds: R Barth, A Soloway,
Plenum Press, New York, 1993
85. RG Zamenhof, DE Wazer, J Bernard Jr., OK Harling, TA DiPetrillo, H Madoc-Jones, JA
Coderre, A Meek, "Federal & Institutional Approvals Necessary Prior to a U.S. Clinical Trial
of Neutron Capture Therapy," in: Advances in Neutron Capture Therapy, eds: R Barth, A
Soloway, Plenum Press, New York, 1993
86. GR Solares, RG Zamenhof, DE Wazer, TE DiPetrillo, SC Saris, G Cano, OK Harling, H
Madoc- Jones, "Effects of Fractionation of Boron Neutron Capture Therapy in a Mouse
Glioma Model," in: Advances in Neutron Capture Therapy,” eds: R Barth, A Soloway,
Plenum Press, New York, 1993
87. OK Harling, R Rogus, R Choi, D Moulin, J Yanch, R Zamenhof, "Dosimetry & Dose
Control for Patient BNCT Trials at the MITR-II Research Reactor," in: Topics in Dosimetry
& Treatment Planning for Neutron Capture Therapy, eds: RG Zamenhof, GR Solares, OK
Harling, Advanced Medical Publishing Inc., Madison, WI, 1994
88. G Solares, R Zamenhof, J Palano, G Cano, "Microdosimetry of Neutron Capture Therapy by
Combination of Histological and Monte Carlo Analysis," in: Topics in Dosimetry &
Treatment Planning for Neutron Capture Therapy, eds: RG Zamenhof, GR Solares, OK
Harling, Advanced Medical Publishing Inc., Madison, WI, 1994
89. Madoc-Jones, RG Zamenhof, G Solares, OK Harling, C-S Yam, K Riley, D Wazer, G
Rogers, M Atkins, “A Phase-I Dose-Escalation Trial of Boron Neutron Capture Therapy for
Subjects with Metastatic Subcutaneous Melanoma of the Extremities,” Proc. 5th. Int. Mtg. on
Prog. in RadioOncology, Salzburg, May 10-14, 1995
90. H Madoc-Jones, R Zamenhof, G Solares, O Harling, C-S Yam, K Riley, S Kiger, D Wazer,
G Rogers, M Atkins, “A Phase-I Dose Escalation Trial of Boron Neutron Capture Therapy
for Subjects with Metastatic Subcutaneous Melanoma of the Extremities,” in: Cancer
Neutron Capture Therapy, ed: Y Mishima, Plenum Press, New York, 1996
91. G Solares, S Kiger, R Zamenhof, “Microdosimetry Studies at the Harvard/MIT Phase-I
Clinical Trial of Boron Neutron Capture Therapy,” in: Advances in Neutron Capture
Therapy, eds: B Larsson, J Crawford, R Weinreich, Elsevier, Amsterdam, 1997
92. RG Zamenhof, GR Solares, WS Kiger, III, EL Redmond, PM Busse, C-S Yam,
“MacNCTPLAN: An Improved Macintosh-based Treatment Planning Program for Boron
Neutron Capture Therapy,” in: Advances in Neutron Capture Therapy, eds: B Larsson,
Crawford, R Weinreich, Elsevier, Amsterdam, 1997
93. G Solares, D Katz, O Harling, R Zamenhof, “On-line Dosimetry for Boron Neutron Capture
Therapy at the MIT Research Reactor,” in: Advances in Neutron Capture Therapy, eds: B
Larsson, J Crawford, R Weinreich, Elsevier, Amsterdam, 1997
94. PM Busse, RG Zamenhof, H Madoc-Jones, GR Solares, S Kiger, III, K Riley, C Chuang, G
Rogers, O Harling, “Clinical Follow-Up of Patients with Melanoma of the Extremity Treated
in a Phase-I Boron Neutron Capture Therapy Protocol,” in: Advances in Neutron Capture
Therapy, eds: B Larsson, J Crawford, R Weinreich, Elsevier, Amsterdam, 1997
95. DT Ingersoll, CO Slater, EL Redmond II, RG Zamenhof, “Comparison of TORT & MCNP
Dose Calculations for BNCT Treatment Planning,” in: Advances in Neutron Capture
Therapy, eds: B Larsson, J Crawford, R Weinreich, Elsevier, Amsterdam, 1997
96. PM Busse, RG Zamenhof, OK Harling, I Kaplan, J Kaplan, C Chuang, J Goorley, WS Kiger
III, K Riley, L Tang, GR Solares, M Palmer, “The Harvard-MIT BNCT Program: overview
of clinical trials and translational research.” Proceedings of the Eleventh International
Congress of Radiation Research; Dublin, U.K., pp. 702-5, 1999
97. MR Palmer, JT Goorley, WS Kiger III, PM Busse, & RG Zamenhof, “Treatment planning
and dosimetry for the Harvard-MIT phase I clinical trial for cranial BNCT.” Proceedings of
the 9th International Symposium on Neutron Capture Therapy for Cancer, Osaka, Japan,
2000
98. GA Santa Cruz, MR Palmer, WS Kiger III, E Matatagui, & R.G. Zamenhof, “A new
probabilistic approach to the microdosimetry of BNCT,” Proceedings of the 9th International
Symposium on Neutron Capture Therapy for Cancer, Osaka, Japan, October 2000
99. WS Kiger III, MR Palmer, RG Zamenhof, PM Busse. “Boron uptake by erythrocytes
following boronophenylalanine-fructose infusion in humans.” Proceedings of the 9th
International Symposium on Neutron Capture Therapy for Cancer, Osaka, Japan, October
2000
100. PM Busse, OK Harling, MR Palmer, I Kaplan, TH Newton Jr, J Kaplan, CF Chuang, WS
Kiger III, KJ Riley, JT Goorley, RG Zamenhof.
“A phase-I clinical trial for cranial bnct at Harvard-MIT.” Proceedings of the 9th
International Symposium on Neutron Capture Therapy, Osaka, Japan, October 2000
101. RG Zamenhof, H Patel, MR Palmer, O Harling, PJ Binns, KJ Riley, J Bernard, H-C Lin,
P.M. Busse, “A core laboratory for the evaluation of new boron compounds: A service to
the NCT community.” Proceedings of the 9th International Symposium on Neutron
Capture Therapy for Cancer, Osaka, Japan, October 2000
102. JF Copeland, CS Melhus, R Horton, V Venkatakrishnan, RG Zamenhof, “Practical quality
control standards for digital display monitors,” Medical Iimaging 2000: Image Display &
Visualization, ed: SK Mun, Proc. Of SPIE, vol. 3976, 2000
103. PM Busse, I Kaplan, RG Zamenhof, OK Harling, J Kaplan, CJ Chuang, JT Goorley, K
Riley, L Tang, GR Solares, MR Palmer, “Boron Neutron Capture Therapy for
Glioblastoma Multiforme & Intracranial Melanoma: Clinical Results of the Harvard-MIT
Phase-I Trial,” in: Frontiers in Neutron Capture Therapy, eds: MF Hawthorn et al, Kluwer/
Plenum Publishers, New York, 2001
104. C Zuo, PV Prasad, N Adnani, L Tang, R Zamenhof, “Spectroscopic Technique for
Measuring BPA Pharmacokinetics: a Preliminary Study,” in: Frontiers in Neutron Capture
Therapy, eds: MF Hawthorn et al, Kluwer/Plenum Publishers, New York, 2001
105. CJ Chuang PM Busse, RG Zamenhof, P Thomas, “Selective Tumor Uptake of
p,Boronophenylalanine- Fructose in an Animal Model of Hepatic Colorectal Metastases,,”
in: Frontiers in Neutron Capture Therapy, eds: MF Hawthorn et al, Kluwer/Plenum
Publishers, New York, 2001
106. PM Busse, RG Zamenhof, I Kaplan, J Kaplan, OK Harling, CJ Chuang, JT Goorley, WS
Kiger, K Riley, L Tang, GR Solares, MR Palmer, “Complete Response of Cutaneous &
Intracranial Melanoma to Boron Neutron Capture Therapy,” in: Frontiers in Neutron
Capture Therapy, eds: MF Hawthorn et al, Kluwer/Plenum Publishers, New York, 2001
107. CJ Chuang, MR Palmer, L Tang, PM Busse, RG Zamenhof, “Predicting B-10
Concentrations in Normal Brain & Glioblastoma from Blood Measurements,” in: Frontiers
in Neutron Capture Therapy, eds: MF Hawthorn et al, Kluwer/Plenum Publishers,
New York, 2001
108. CJ Chuang, MR Palmer, L Tang, PM Busse, RG Zamenhof, “Time-Dependent
Biodistribution of BPA-f in Normal & Tumor Brain Tissues in Mice,” in: Frontiers in
Neutron Capture Therapy, eds: MF Hawthorn et al, Kluwer/Plenum Publishers, New
York, 2001
109. MR Palmer, WS Kiger, C Zuo, LP Panych, CRG Guttmann, RG Zamenhof, PM Busse,
“Integrated Medical Image Registration, Patient Positioning, & Patient Monitoriong for
Cranial BNCT,” in: Frontiers in Neutron Capture Therapy, eds: MF Hawthorn et al,
Kluwer/Plenum Publishers, New York, 2001
110. T Goorley, J Capala, WS Kiger, RG Zamenhof, MR Palmer, PM Busse, F Wheeler, D
Nigg,“A Comparison of two BNCT Treatment Planning Programs: BNCT-RTPE & Mac
NCTPLAN,” in: Frontiers in Neutron Capture Therapy, eds: MF Hawthorn et al, Kluwer/
Plenum Publishers, New York, 2001
111. WS Kiger, RG Zamenhof, “Application of Realistic Microdosimetry Techniques to the
Radiobiology of BNCT,” in: Frontiers in Neutron Capture Therapy, eds: MF Hawthorn et
al, Kluwer/Plenum Publishers, New York, 2001
112. WS Kiger, KJ Riley, MR Palmer, RG Zamenhof, “A Validated Pharmacokinetic Model for
the Concentration of B-10 in Blood following BPA-f Administration in Humans,” in:
Frontiers in Neutron Capture Therapy, eds: MF Hawthorn et al, Kluwer/Plenum Publishers,
New York, 2001
113. T Goorley, WS Kiger III, RG Zamenhof, “Comparison of Snyder Head Phantom Models
Used for Neutron Capture Therapy Benchmark Monte Carlo Dosimetry Calculations,” in
Advanced Monte Carlo for Radiation Physics, Particle Transport Simulation and
Applications. Ed. A Kling, F Barao, M Nakagawa, L Tavora, P Vaz, Springer, Berlin, 2001
114. SJ Gonzalez, GA Santa Cruz, WS Kiger, JT Goorley, MR Palmer, PM Busse, RG
Zamenhof, “NCTPlan, the New PC Version of MacNCTPlan: Improvements and
Verification of a BNCT Treatment Planning System,” in: Research and Development in
Neutron Capture Therapy. Eds: W Sauerwein et al. Monduzzi Editore, Bologna, 2002
115. F-Y Hsu, MR Palmer, WS Kiger III, GA Santa Cruz, SJ Gonzalez, PM Busse, R Zamenhof,
“Comparison of Two BNCT Treatment Planning Codes: NCTPlan and MacNCTPlan,” in:
Research and Development in Neutron Capture Therapy. Eds: W Sauerwein et al.
Monduzzi Editore, Bologna, 2002
116. WS Kiger III, GA Santa Cruz, SJ Gonzalez, F-Y Hsu, KJ Riley, PJ Binns, OK Harling, MR
Palmer, PM Busse, RG Zamenhof, “Verification and Validation of the NCTPlan Treatment
Planning Program,” in: Research and Development in Neutron Capture Therapy. Eds: W
Sauerwein et al. Monduzzi Editore, Bologna, 2002
117. SJ Gonzalez, GA Santa Cruz, WS Kiger III, RG Zamenhof, “A New Computational Tool
for Constructing Dose-Volume Histograms Using Combinatorial Techniques,” in: Research
and Development in Neutron Capture Therapy. Eds: W Sauerwein et al. Monduzzi Editore,
Bologna, 2002
118. WS Kiger III, PL Micca, JA Coderre, RG Zamenhof, “Microdosimetry Analysis of the
10B(n,α)7Li Reaction for Human and Rat Neural Tissues and Tumor,” in: Research and
Development in Neutron Capture Therapy. Eds: W Sauerwein et al. Monduzzi Editore,
Bologna, 2002
119. GA Santa Cruz, RG Zamenhof, “A Theoretical Formalism to Extrapolate Measured CBE
Factors to Different Conditions of Geometry and B-10 Distribution,” in: Research and
Development in Neutron Capture Therapy. Eds: W Sauerwein et al. Monduzzi Editore,
Bologna, 2002
120. WS Kiger III, CF Chuang, MR Palmer, RG Zamenhof, PM Busse, “Pharmacokinetic
Modeling of BPA-F in Murine Glioma and Melanoma Models for NCT,” in: Research and
Development in Neutron Capture Therapy. Eds: W Sauerwein et al. Monduzzi Editore,
Bologna, 2002
121. WS Kiger, MR Palmer, KJ Riley, RG Zamenhof, PM Busse, “Pharmacokinetic Modeling
for Borobophenylalanine-Fructose Mediated Neutron Capture Therapy: B-10 Concentration
Predictions and Dosimetric Consequences,” in: Research and Development in Neutron
Capture Therapy. Eds: W Sauerwein et al. Monduzzi Editore, Bologna, 2002
122. PM Busse, OK Harling, MR Palmer, WS Kiger III J Kaplan, I Kaplan, CF Chuang, JT
Goorley, KJ Riley, TH Newton, GA Santa Cruz, X-Q Lu, RG Zamenhof, “A Critical
Examination of the Results grom the Harvard-MIT Program Phase I Clinical Trial of NCT
For Intracranial Disease,” in: Research and Development in Neutron Capture Therapy. Eds:
W Sauerwein et al. Monduzzi Editore, Bologna, 2002
123. MJ Rivard, RG Zamenhof, “Moderated Cf-252 neutron energy spectra in brain tissue and
calculated boron-neutron capture dose,” Radiation Research, 61:753-757, 2004
124. FY Hsu, CJ Tung, JC Chen, YL Wang, HC Huang, RG Zamenhof, “Dose-rate scaling factor
estimation for THOR BNCT test beam.” Radiation Research, 61:881-885, 2004
125. WS Kiger, XQ Lu, OK Harling, KJ Riley, PJ Binns, J Kaplan, H Patel, RG Zamenhof, Y
Shibata, ID Kaplan, PM Busse, MR Palmer, “Preliminary treatment planning & dosimetry
for a clinical trial of neutron capture therapy using a fission converter epithermal neutron
beam.” Radiation Research, 61:1075-1081, 2004
126. A Wittig, R Zamenhof, et al., “Boron analysis and boron imaging in biological materials for
boron neutron capture therapy”, Crit. Rev. Oncol./Hematol. (2008)
3. TECHNICAL/SCIENTIFIC REPORTS & EDUCATIONAL MATERIALS
127. RG Zamenhof, BW Murray, OL Deutsch, RI Pettigrew, RA Rydin, GL Brownell: "New
Approaches to the Dosimetry of Boron Neutron Capture Therapy at MIT and MGH," in:
Biomedical Dosimetry; IAEA SM-188, pg. 179-184, IAEA, Vienna, March, 1975
128. RG Zamenhof, MJ Homer: "Mammography: Part 1. Physical Principles," Appl. Rad., Vol.
13, No. 5, pp. 134-140, 1984
129. RG Zamenhof, MJ Homer: "Mammography: Part 2. Equipment Selection", Appl. Rad., Vol.
13, No. 6, pp. 230-234, 1984
130. JS Robertson, MJ Berger, JP Jones, KA Lathrop, JW Poston, KN Vanek, RG Zamenhof,
"The Experimental Basis for Absorbed Dose Calculations in Medical Uses of
Radionuclides", NCRP Rep. No. 83, NCRP, Bethesda, MD, 1985
131. OK Harling, JA Bernard, RG Zamenhof, H Madoc-Jones, "A Clinical Trial of Neutron
Capture Therapy for Brain Tumors," in: Utilization of Multi-Purpose Research Reactors,
IAEA SM-300, Vienna, 1988
132. RG Zamenhof, "Mammography," in: Encyclopedia of Medical Instrumentation and
Devices, John Wiley and Son, New York, 1988
133. RG Zamenhof, "Techniques for Bone Mineral Measurement," in: Radiology, Diagnosis,
Imaging, Intervention, Eds: JM Taveras, JT Ferrucci, John Wiley & Son, New York, 1988
134. OK Harling, JA Bernard, RG Zamenhof, "Critique of MIT Workshop on Neutron Beam
Design, Development, and Performance for Neutron Capture Therapy," in: Progress in
Neutron Capture Therapy for Cancer, eds: B Allen, D Moore, B Harrington, New York,
Plenum Press, 1992
135. RG Zamenhof, “Subject in Review: Health Hazards of Low-Frequency Electromagnetic
Fields,” Pediatric Alert, 21:51-54, 1993
4. BOOKS, BOOK CHAPTERS & MONOGRAPHS
136. GL Brownell, JA Correia, RG Zamenhof: "Positron Instrumentation", in: Recent Advances
in Nuclear Medicine, vol. 5, ed. JE Lawrence and TF Budinger, Grune and Stratton, New
York, 1978
137. GL Brownell, RG Zamenhof, BW Murray, and GR Wellum: "Boron Neutron Capture
Therapy", in: Therapy in Nuclear Medicine, ed. RP Spencer, Grune and Stratton, New
York, 1978
138. GR Wellum, RG Zamenhof, EI Tolpin, "An Analysis of the Possible Use of Boron Loaded
Tumor- Associated Antibodies in Boron Neutron Capture Therapy", in: Synthesis and
Applications of Isotopically Labelled Compounds, ed: WP Duncan, Elsevier, New York,
1983
139. JE Kirsch, GL Brownell, RG Zamenhof, WH Sweet, JR Messer, EP Richardson, A
Takeuchi, H Hatanaka, "Irradiation of Normal Canine Brain After Craniectomy," in:
Neutron Capture Therapy for Brain Tumors, ed: H Hatanaka, Nishimura, Japan, 1986
140. OK Harling, JA Bernard, RG Zamenhof, "Neutron Beam Design, Development, and
Performance for Neutron Capture Therapy," Plenum Press, New York, 1990
141. D Wazer, R Zamenhof, H Madoc-Jones, O Harling, "Boron Neutron Capture Therapy,"
Chapter VII in: "Radiation Oncology: Technology and Biology," eds. P Mauch and J
Loeffler, New York, Saunders, 1994
142. RG Zamenhof, GR Solares, OK Harling (eds.), “Topics in Dosimetry & Treatment Planning
for Neutron Capture Therapy, Advanced Medical Publishing Inc., Madison, WI, ISBN: 1
883526-02-7, 1994
143. RG Zamenhof, AR Bogdan. “Basic Image Formatting and Software Functions”. in:
Computed Tomography. ed: Richard H. Behrman, Clinical Communications, Inc.,
Greenwich, CT, 1995
144. RG Zamenhof, RH Behrman. “Quantitative CT,” in: Computed Tomography. ed: RH
Behrman, Clinical Communications, Inc., Greenwich, CT, 1995
145. D Wazer, R Zamenhof, H Madoc-Jones, O Harling, "Boron Neutron Capture Therapy,"
Chapter XII in: "Cancer of the Nervous System," eds: P Black and J Loeffler, Cambridge,
MA, Blackwell Science, 1996
146. R Zamenhof, PM Busse, OK Harling, T Goorley, “Boron Neutron Capture Therapy,” in:
The Modern Technology of Radiation Oncology: A Compendium for Medical Physicists
and Radiation Oncologists," ed: J VanDyk, Medical Physics Publishing, Madison, WI, 1999
147. D Rorer, A Wambersie G Whitmore, RG Zamenhof, “Current Status of Neutron Capture
Therapy,” IAEA-Tecdoc, IAEA, Vienna, 2001
148. RG Zamenhof, MR Palmer, PM Busse, “Clinical Treatment Planning for Subjects
Undergoing Boron Neutron Capture Therapy at Harvard-MIT,” in: Current Status of
Neutron Capture Therapy, Eds: D Rorer, A Wambersie G Whitmore, RG Zamenhof, IAEA
Tecdoc-1223, ISSN-1011-4289, IAEA, Vienna, 2001
149. S Green, R Zamenhof, “Radiation Measurements,” in: Practical Radiation Protection
Measurements, Ed: C Martin & D Sutton, Oxford University Press, London, U.K., 2002
150. AB Wolbarst, RG Zamenhof, W Hendee (eds), “Advances in Medical Physics” Medical
Physics Publishing, Madison, WI, 2006
5. PhD THESIS
MIT NUCLEAR ENGINEERING DEPARTMENT & HARVARD-
MIT JOINT PROGRAM IN HEALTH SCIENCE TECHNOLOGY
RG Zamenhof, "The Measurement of Total Body Elemental Composition by Prompt
Gamma Neutron Activation Analysis." Doctoral Thesis, Massachusetts Institute of
Technology, Department of Nuclear Engineering, U.S. Library of Congress No. 186233,
1977 [Supervisor: Professor Gordon L. Brownell, Dept. Nuclear Engineering, MIT]
6. BOOK REVIEWS
1. R Zamenhof, Med. Phys., 7:577, 1980
2. R Zamenhof, AJR 8:408, 1993
3. R Zamenhof, AJR 164:870, 1995
7. LETTERS TO JOURNAL EDITORS
1. R Zamenhof, "Contrast-Detail Diagrams for the Evaluation of CT Scanner Performance",
A.J.R., 135:1313, 1980
2. R Zamenhof, "Using a CT Scanner to Measure Temperature In Vivo", Med. Phys., 10:111, 1983
3. R Zamenhof, “Non-invasive thermometry with a clinical x-ray CT scanner”, Medical
Physics, 10:374, 1983
4. Y Maruyama, J Wierzbicki, M Ashtari, RJ Yaes, JL Beach, J Yanch, R Zamenhof, CB
Schroy, "Cf- 252 Neutron Capture Therapy & Teletherapy," Int. J. Rad. Onc. Biol. Phys.,
23:255, 1992
5. R Zamenhof, A Kalend, W Bloomer, "Looking for a Few Good Molecules," J. Nat. Cancer
Inst., Vol. 84, 16:1290, 1992
6. J Wierzbicki, R Zamenhof, “Comment on Monte Carlo Simulation of Cf-252 Dose
Distribution Brachytherapy,” Med. Phys. 24:8, 1997
7. R Zamenhof, comment on the recent editorial "Is there a Future for Neutron Capture
Therapy?" Int. J. Rad. Onc. Biol. Phys., 1997
8. PATENTS & COPYRIGHTS
1. RG Zamenhof, GR Solares, “High-Resolution Track-Etch Autoradiography”, U.S. Patent
#5,296,090, awarded March, 1994
2. RG Zamenhof, “Monte Carlo Based Treatment Planning for Neutron Capture Therapy”,
U.S. Patent #5,341292, awarded August, 1994
3. RG Zamenhof, RADCOMP®, a software program for diagnostic X-ray exposure
calculations, copyrighted and marketed under royalty agreement by Nuclear Associates, Inc.,
Carle Place, NY, 1984
4. RG Zamenhof, “Contrast-Enhanced Dual-Energy Subtraction Mammography”
(utility patent submitted May 16, 2018)
5. RG Zamenhof, “Deuteron therapy” (utility patent submitted February 6, 2020)
6. RG Zamenhof, Improved Iodine Contrast-Enhanced Energy Subtraction Mammography”
(utility patent submitted May 15, 2020)
9. SOFTWARE WRITTEN FOR PUBLIC DOWNLOAD
1. POLYFIT MAC
www.dropbox.com/s/n0wn4fxygxb0lia/FittingTools_MacOSX.zip?dl=0
2. POLYFIT WINDOWS
www.dropbox.com/s/x39ihoja8xp5kio/FittingTools_Win.rar?dl=0
3. POLYFIT USER’S MANUAL
www.dropbox.com/s/g3xz78082zqxwxy/PolyFit%201.1%20User%27s%20Manual.pdf?dl=0
4. RADCOMP WINDOWS
www.dropbox.com/s/e13yrpzkhype7n9/RadComp.zip?dl=0
5. RADCOMP USER’S MANUAL
www.dropbox.com/s/g3m4rk00hm809d6/RadComp4.2%20User%20Manual.pdf?dl=0
NON-ACADEMIC PUBLICATIONS
Author of bi-weekly Science Column for the Vermont Standard newspaper, 2018-2020
Author of “The Adventures of Armadillo Baby and Annabelli”, an illustrated children’s book, 2nd Ed., published by Old Johnson Place Publishing, 2018.
Author of “Seventeen Fun Science Articles”, published by Amazon Books, 2020
Author of “The Continuing Adventures of Armadillo Baby & Annabelli: In Which a Horse Teaches a Camel Dressage”, published by Amazon Books, 2022
ATTESTATION
To the best of my knowledge the facts stated in this resumé are accurate
